Binding of 13C-enriched oleic acid to bovine serum albumin and to three large proteolytic fragments of albumin--two complementary fragments corresponding to the two halves of albumin and one fragment corresponding to the carboxyl-terminal domain--yielded unique patterns of NMR resonances (chemical shifts and relative intensities) that were used to identify the locations of binding of the first ...

Introduction. Edible oils containing > 60 % monoenoic acids (i. e. oleic acid), in particular olive oil and Canola oil have been shown to exhibit beneficial effects on lipid metabolism in human (LDL-cholesterol blood levels, triacylglycerol blood levels) within the last few years [1]. These findings are in contrast to earlier recommandations by nutrition experts who strongly favored high-linole...

Fatty acids are essential components of the dynamic lipid metabolism in cells. Fatty acids can also signal to intracellular pathways to trigger a broad range of cellular responses. Oleic acid is an abundant monounsaturated omega-9 fatty acid that impinges on different biological processes, but the mechanisms of action are not completely understood. Here, we report that oleic acid stimulates the...

The metabolic fate of (14)C-labeled fatty acids which have been incubated with human platelets, has been traced. The following has been shown. (a) Intact platelets have a considerable capacity to oxidize fatty acids. (b) When tracer amounts of four of the most common fatty acids in normal plasma were incubated with platelets, each showed a distinctive pattern of uptake among neutral lipids and ...

The uptake of C-labeled oleic acid and its incorporation into combined lipids by aortic intimas from normal and cholesterol-fed rabbits has been investigated in vitro. More than five times as much oleic acid was taken up by the atherosclerotic intima as by the normal intima. About twice as much oleic acid was incorporated into phospholipid, and twenty times as much into cholesterol ester by the...

Cobalt ferrite (CoFe2 O4 ) nanoparticles have attracted significantly attentions for spintronics, recording media and bioapplications due to their unique magnetic and chemical properties. In this work, single phase CoFe2 O4 nanoparticles were synthesized at various coprecipitation temperatures (60, 80 and 90 °C) without post calcination. The effects of oleic acid as surfactant on the microstruc...

Gastric cancer and breast cancer have a clear tendency toward metastasis and invasion to the microenvironment predominantly composed of adipocytes. Oleic acid is an abundant monounsaturated fatty acid that releases from adipocytes and impinges on different energy metabolism responses. The effect and underlying mechanisms of oleic acid on highly metastatic cancer cells are not completely underst...

The present work shows that when mitochondrial beta-oxidation is stimulated by the hypolipemic, non-beta-oxidizable fatty acid analogue tetradecylthioacetic acid, there is a decrease in the secretion of triacylglycerol in cultured rat hepatocytes. In order to study the effects of tetradecylthioacetic acid in cells with different fatty acid oxidation rates, cells were grown without or with L-car...

cofe2o4 have been synthesized via a surfactant assisted gel microwave route with a molar ratio of fe/co= 2 and oleic acid (oa) was used as a surfactant. fourier transform infrared spectroscopy (ftir), x-ray diffraction (xrd) and scanning electron microscopy (sem) were used to consider the structural and morphological properties of cofe2o4 nano-particles. results demonstrated that oleic acid is ...

the available minoxidil formulations for topical application suffer with major drawback having less contact time with the scalp which requires repeated application. hence, the present study was aimed to investigate the effect of microemulsions and microemulsion based hydrogel systems (mehs) for increased percutaneous penetration of minoxidil. minoxidil microemulsions were developed by following...