background: pre-clinical investigation of stem cells for repairing damaged myocardium predominantly used rodents, however large animals have cardiac circulation closely resembling the human heart. the aim of this study was to evaluate whether spect/ct myocardial perfusion imaging (mpi) could be used for assessing sheep myocardium following an acute myocardial infarction (mi) and response to int...

We describe the parallel full-f gyrokinetic particle-in-cell plasma simulation code ELMFIRE and the issue of solving a electrostatic potential from particle data distributed across several MPI (Message Passing Interface) processes. The potential is solved through a linear system with a strongly sparse matrix and ELMFIRE stores data of the estimated nonzero diagonals of the whole matrix in every...

Vasodilator stress myocardial perfusion imaging (MPI) accounts for up to 50% of all stress MPI studies performed in the U.S. In 2008, the Food and Drug Administration approved regadenoson for stress testing in conjunction with MPI. Regadenoson, unlike adenosine, is a selective A(2A) agonist that is given as an intravenous bolus at a fixed dose, with less undesirable side effects including atrio...

The realization of support for workstation clusters with the integrated tool environment Annai is discussed in this paper. Annai prototypes developed at CSCS supportparallel program developmentwith standard paradigms: implicitlyparallel High Performance Fortran (HPF) and explicit communication with the Message Passing Interface (MPI). The port to this new platform required only minor changes to...

A real-world example of adding OpenACC to a legacy MPI FORTRAN Preconditioned Conjugate Gradient code is described, and timing results for multi-node multi-GPU runs are shown. The code is used to obtain three-dimensional spherical solutions to the Laplace equation. Its application is finding potential field solutions of the solar corona, a useful tool in space weather modeling. We highlight key...

MPI applications typically are designed to be run on a parallel machine with one process per core. If processes exhibit different computational load, either the code must be rewritten for load balancing, with negative side-effects on readability and maintainability, or the one-process-per-core philosophy leads to a low utilization of many processor cores. If several processes are mapped per cor...

Background We evaluated early and late pulmonary hypertension (PH) in preterm infants and its relation with bronchopulmonary dysplasia (BPD). Methods Sixty-seven preterm infants < 30 weeks' gestation underwent echocardiography within 14 days after birth for early PH and over 28 days after birth for late PH. We measured tricuspid regurgitation (TR) peak velocity, pulse Doppler-derived myocardi...

In this paper we make the case for adding standard nonblocking collective operations to the MPI standard. The non-blocking point-to-point and blocking collective operations currently defined by MPI provide important performance and abstraction benefits. To allow these benefits to be simultaneously realized, we present an application programming interface for non-blocking collective operations i...

Manually tuning MPI runtime parameters is a practice commonly employed to optimise MPI application performance on a specific architecture. However, the best setting for these parameters not only depends on the underlying system but also on the application itself and its input data. This paper introduces a novel approach based on machine learning techniques to estimate the values of MPI runtime ...

To determine the transmissibility of chronic wasting disease (CWD) to sheep, 8 Suffolk lambs of various prion protein genotypes (4 ARQ/ARR, 3 ARQ/ARQ, 1 ARQ/VRQ at codons 136, 154, and 171, respectively) were inoculated intracerebrally with brain suspension from mule deer with CWD (CWDmd). Two other lambs were kept as noninoculated controls. Within 36 months postinoculation (MPI), 2 inoculated ...