Glaucoma is the second highest cause of blindness worldwide with an estimated half of the glaucoma population unaware of their disease. To date, intraocular pressure is the most important modifiable risk factor and lowering it has been proven to reduce progression of visual field loss associated with glaucoma. Different strategies are available to lower intraocular pressure and include medical,...

Purpose To examine the factors associated with blindness from primary open-angle glaucoma (POAG) among black and white patients at our institution. Patients and methods For this retrospective, case-control study, patients legally blind from POAG ("cases") were matched on age, race, and gender with non-blind POAG patients ("controls"). Thirty-seven black case-control pairs and 19 white case-co...

AIM To present, through a thorough literature research, current and older scientific efforts to investigate the putative association between Alzheimer's disease (AD) and glaucoma, especially primary open-angle glaucoma (POAG). METHODS We included in our review article epidemiological, experimental and clinical laboratory studies. RESULTS While many authors support the existence of a strong ...

The epidemiology of eye Disease, 3rd edition, edited by Johnson GJ et al. The third edition of this authoritative text is 240 pages longer than the previous version and has 15 additional expert contributors. There is an extra chapter on research synthesis and an expanded section on visual impairment and blindness in children. Dry eye and uveitis now feature as separate entities, and the final t...

PURPOSE To assess the level of plasma glutathione in patients with untreated primary open-angle glaucoma. METHODS Twenty-one patients with newly diagnosed primary open-angle glaucoma and 34 age- and gender-matched control subjects were subjected to a blood analysis to detect the level of circulating glutathione in its reduced and oxidized forms. The effect of age, gender, and systemic blood p...

AIMS To assess the Tuck-Crick and the Quigley-Vitale predictive regression equations against fresh independent real world data for estimating the prevalence of primary open angle glaucoma (POAG) in the UK. To apply the equations to the elderly population of England and Wales, for which there is sample survey data on glaucoma, and demographic data. METHODS Directly measured actual prevalence o...

[This corrects the article DOI: 10.1371/journal.pone.0191185.].

OBJECTIVES (i) To determine the prevalence and pattern of glaucomas presented to Nepal Eye Hospital for strategic planning. (ii) To know the most common attributable factors giving rise to secondary glaucoma. (iii) To know the incidence of Glaucoma blindness. MATERIALS AND METHODS A retrospective hospital based analysis of medical records of patients attending Nepal Eye Hospital Glaucoma clin...

A recording medication monitor and fluorescein technique were used to study self-medication by 82 patients with primary open-angle glaucoma for whom pilocarpine eye drops 3 times a day had been prescribed. Of these patients 34 (41%) missed 6 or more doses during a 20-day period, and for 35 (43%) an 8-hour dose interval was exceeded at least 20% of the time. Consequences may include lack of effe...

Purpose. To evaluate gel microstent (XEN, Aquesys, Inc) for treatment of primary open angle glaucoma (POAG). Methods. In this prospective interventional study, 13 eyes with POAG underwent XEN implantation with subconjunctival mitomycin-C. Of those eyes, 3 were pseudophakic and 10 underwent simultaneous phacoemulsification and XEN. Patients had uncontrolled IOP, had intolerance to therapy, or ha...