Treating pain in burn patients with a history of opioid or drug abuse is challenging. There no consensus on management for usage. Our aim was to study the association previous addiction and treatment acute patients, focusing daily morphine milligram equivalent (MME) requirements outcomes. We compared (group 1) without 2) who were admitted an American Burn Association verified center using Premi...

opium is one of the oldest herbal medicines currently used as an analgesic, sedative and antidiarrheal treatment. the effects of opium are principally mediated by the μ -,κ- and δ-opioid receptors. opioid substances consist of all natural and synthetic alkaloids that are derived from opium. most of their effects on gastrointestinal motility and secretion result from suppression of neural activi...

When women addicted to opioids seek prenatal care, the treatment of choice is methadone. Methadone mediates the addiction by reducing fluctuations in maternal serum opioid levels and protecting the fetus from repeated withdrawal episodes. Methadone maintenance is associated with increased maternal weight gain, decreased illegal drug use, and improved compliance with prenatal care. Although the ...

introduction: association between single-nucleotide polymorphisms (snps) in mu opioid receptor gene and drug addiction has been shown in various studies. here, we have evaluated the existence of polymorphisms in exon 3 of this gene in iranian population and investigated the possible association between these mutations and opioid addiction.  methods: 79 opioid-dependent subjects (55 males, 24 fe...

Abstract Introduction Laparoscopic TAP block has been used in various surgical subspecialties to reduce postoperative opioid requirement and hence its side effects. The aim of our study was evaluate the effect laparoscopic bariatric surgery. Methods We performed a retrospective analysis patients who underwent surgery by two surgeons at metropolitan public hospital from January 2019 March 2020. ...

conclusions a modified tool to assess methadone treatment response serves to identify patients at high-risk for relapse at a minimal cost, as well as evaluate the relevant physical and psycho-social domains affecting opioid-dependent patients. the great will serve as a useful adjunct to regular clinical assessments, allowing clinicians and researchers to properly assess opioid addiction patient...

This policy brief reviews the evidence to date on providing antiretroviral (ARV) therapy to HIV-positive injecting drug users. A number of related medical, psychological and social issues are also addressed including the need to manage drug interactions and the benefi t of harm reduction interventions in supporting optimum care for HIV-positive injecting drug users. General issues related to HI...