BACKGROUND Today, the society's need to find the roots of a few thousand-year old substance abuse and the drugs addiction crisis has increased to the extent that it has become a problem within our country. The problem of substance dependence is not only about drug abuse, but it is actually the interrelationship of the person and the dependency on drugs. This study aimed to compare early maladap...

INTRODUCTION The number of cases of lead poisoning (LP), a widely known disease with various aetiologies, being reported globally has decreased over the years due to both limited domestic applications of lead and enforcement of stringent safety measures. However, a new presentation of lead poisoning, lead-contaminated opium (LCO), is gradually emerging in our region. This study aimed to determi...

intraperitoneal adhesion formation is a major cause of intestinal obstruction and inferlitity.previous abdominal or pelvic surgery are the most common causes of intraperitoneal adhesion formation.addiction to opium and moephine is not only an important social and individual problem in the world but also affects human physiology and immune system.this randomized double-blind study was designed t...

Background: Although the triggering role of both opium use and elevated plasma homocysteine level for progressing atherosclerosis and, therefore, appearing coronary heart disease has been clearly determined, no study are available with respect to the relation between these to risk profiles. In the present study and for the first time, we hypothesized that the opium addiction can be potentially ...

Introduction: Addiction imposes a large medical, social and economic burden on societies. Currently, there is no effective treatment for addiction. Our struggle to decipher the different mechanisms involved in addiction requires a proper understanding of the brain regions which promote this devastating behavior. Previous studies have shown a pivotal role for insula in cigarette smoking. In this...

Background & Aims: This study was carried out to assess the effect of opium addiction on the incidence of different types of arrhythmias after acute myocardial infarction (AMI). Methods: The study population consisted of 200 patients with first AMI admitted within 6 hours of the onset of chest pain to the coronary care units (CCU) of two hospitals affiliated to Kerman University of Medical Scie...

A survey on opium use was earned out in Tinsukia district of upper Assam to assess the present prevalence and pattern of opium abuse and compared with earlier findings of the year 1981 (Baruah et al., 1995). A total of 75 addicts could be detected during the survey and 61 were interviewed using structured questionnaire. The results indicate significant decline in prevalence in opium use over th...

BACKGROUND Regarding the limited studies about effects of addiction on coagulation factors as a risk factor for increasing coagulation, and its relation to coronary artery disease, we decided to investigate the effect of opium on inflammatory and coagulation factors in a controlled setting. METHODS This case-control study was performed using two groups of smoking males addicted to opium (27 c...

Background: Addiction is a global public health problem, with over 36 million people suffering from drug-use disorders. Afghanistan, the world’s leading opium producer, has high rates of drug use owing to easy access drugs in this country. This study aimed investigate users’ quality life Herat, and identify factors affecting it. Methods: cross-sectional examined health-related at six rehabilita...