Daun karamunting (Melastoma malabathricum. L) dalam bentuk teh (Tisane) dipreparasi sebagai minuman merupakan salah satu upaya menangani diabetes oleh masyarakat di Kalimantan Barat. Tujuan dari penelitian ini adalah memetakan profil sensori daun dan atribut yang berpotensi menurunkan tingkat kesukaan dengan metode sensometrik. Teh diminati konsumen tidak terlalu bitter kurang astringency. Meto...

OBJECTIVE Metabolomics is the analysis of the global constitution of endogenous metabolites in cells, tissue, and bodily fluids based on analysis techniques with high output, high sensitivity, and high resolution. The physiological and pathological state of the subject investigated could be identified and analyzed through examining metabolite changes. In this study, 1H-NMR metabolomics was empl...

Coffee has a positive effect on health due to its high content of antioxidant compounds. The potential activity coffee is strongly influenced by chemical compound profile. This study aimed analyze the different solvents metabolites profile, activity, and determine relevant functional groups which positively contribute coffee’s activity. In this study, methanolic extract samples from robusta ara...

The MD simulations have been performed using the OPLS force-field [1]. The toluene and phosphine molecules have been treated as fully rigid bodies, whereas the borane molecule has been also parametrized for pyramidalization and aryl torsions. The functional form of the force-field consists of harmonic terms for bond stretching and angle bending, Fourier series for torsional energetics, and Coul...

One-person librarians (OPLs) are the sole information provider in their respective organizations. Continuing professional development (CPD) is vital to satisfy their own information needs and, by proxy, those of the people they serve. No research has so far been carried out to establish what CPD means to these highly specialized library workers. This article reports on some of the findings of a...

Objective. The aim of the study is to investigate serum metabolomics electroacupuncture (EA) with different current intensities in treatment functional constipation (FC). Methods. total number FC patients was 19, (7, 6, low intensity group (LCI), high (HCI), and mosapride citrate tablet control (MC), respectively). Patients EA groups received 16 sessions acupuncture treatments. MC were orally a...

A method for analyzing the protein site similarity was devised aiming at understanding selectivity of homologous proteins and guiding the design of new drugs. The method is based on calculating Cα distances between selected pocket residues and subsequent analysis by multivariate methods. Five closely related serine proteases, the coagulation factors II, VII, IX, X, and XI, were studied and thei...