background: squamous cell carcinoma (scc) is the most common malignancy in oral cavity. angiogenesis is essential for the development and progression of scc. recently, some studies have reported that mast cells may play a role in tumor progression via promoting angiognesis. since the results of various studies on the role of mast cells in tumor progression is not uniform, the aim of this study ...

Verrucous carcinoma (VC) is a rare variant of well differentiated squamous cell carcinoma (SCC) which is usually found in oral cavity mucosa. Cutaneous verrucous carcinoma is a rare entity and in this paper we report a 43 years old man with VC superimposed on chronically inflamed skin of ileostomy site. Previously, he was operated to treat rectal adenocarcinoma and has had ileostomy for six mon...

AIM To characterize the immunohistochemical expression of p27, p21(WAF/Cip1) and p16(INK4a) in normal oral epithelium, oral squamous papilloma and oral squamous cell carcinoma. MATERIALS AND METHODS Immunohistochemical staining for p27, p21(WAF/Cip1) and p16(INK4a) was evaluated in 32 samples of normal oral squamous epithelium, 30 samples of oral squamous papilloma, and 34 samples of oral squ...

BACKGROUND Metastatic carcinoma to the jaws and oral region are very rare, representing less than 1% of all oral tumors. Unfortunately, oral metastasis is usually manifestation of an advanced stage of primary cancer, and indicates widespread disease and poor prognosis. MATERIAL AND METHODS In this retrospective study, a total of 2039 patients with history of oral malignant tumor between 1980 ...

Verrucous carcinoma is an unusual, non-metastasizing, distinct variant of squamous cell carcinoma composed of four subtypes according to the site of occurrence: oral type, anogenital type, plantar type, and other cutaneous sites. Oral type verrucous carcinoma usually shows slow progression with a low incidence of metastases. Treatment of verrcous carcinoma is challenging; multiple medical and s...

Background: Head and neck carcinoma is the malignant lesions which develops on lips, oral cavity, nasal mucosa, paranasal sinuses, inside or outside throat parotid glands. Magnetic resonance imaging can be a good alternative to invasive procedures for detection of metastatic disease in cases head tumors. Objective: To evaluate diagnostic accuracy magnetic detecting metastasis nodes squamous cel...

OBJECTIVE To establish the time trends of the frequency and prevalence of oral cavity cancer in regard to age and gender in a 20-years (time period 1989 - 2008) cohort of Mexicans. DESIGN AND SETTING 13,235 head and neck biopsies from the archive of the Oral Pathology Laboratory, Dental School, National Autonomous University of Mexico were revised. The cases with diagnoses of oral cancer were...

statement of the problem: lichen planus is a mucocutaneous disease that is relatively common in middle aged individuals. some studies have shown that oral lichen planus has a potential to progress to squamous cell carcinoma.p21 is a cyclin-dependent kinase inhibitor that regulates the cell cycle, thus it acts as an inhibitor in cell proliferation. purpose: this study was aimed to evaluate and c...