BACKGROUND Oral lichen planus is a chronic inflammatory disease with a poorly understood etiology. The role of angiogenesis in the development of different chronic inflammatory diseases is of great concern. Vascular endothelial growth factor (VEGF) is an important regulator of angiogenesis. We aimed to evaluate the serum level of VEGF in patients with oral lichen planus compared with normal ind...

Oral lichen planus is a premalignant chronic inflammatory mucosal disorder with unknown etiology. It is a multifactorial disease and in addition to genetic background, infections, stress, drug reactions are suggested as risk factors. Helicobacter pylori which is involved in development of many gastrointestinal lesions may also be implicated in oral lichen planus induction. This is of clear impo...

Oral Lichen Planus is a chronic inflammatory disease of unknown etiology. Erosive/ ulcerative oral lichen planus is often a painful condition that tends to become malignant, urging appropriate therapy. Laser therapy has recently been suggested as a new treatment option without significant side effects. This article presents two cases of erosive/ ulcerative oral lichen planus, who had not receiv...

background & objective: lichen planus is a mucocutaneous disease which is relatively common and in 30-70% of patients, mucosal lesions can be seen and known as a precancerous lesion but its etiology is not completely understood. desmogleins i and iii are the main desmosomal transmembrane proteins. these proteins have been identified as the autoantigen of the autoimmune disease. the aim of t...

Lichen planus is a mucocutaneous disease that predominantly affects older patients and occurs much less frequently in the pediatric population. Furthermore, oral lichen planus is extremely rare in childhood with very few cases cited in the literature. The intention of this paper is to contribute two clinically and histologically documented cases of juvenile oral lichen planus cases to the liter...

CLP: cutaneous lichen planus DIF: direct immunofluorescence dsDNA: double-stranded DNA SLE: systemic lupus erythematosus OLP: oral lichen planus INTRODUCTION Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease that can involve oral mucosal membranes in up to 45% of patients. Oral presentation is commonly described as erythema involving multiple oral sites. Oral ulceration is ...

STATEMENT OF THE PROBLEM Lichen planus is a mucocutaneous disease that is relatively common in middle aged individuals. Some studies have shown that oral lichen planus has a potential to progress to squamous cell carcinoma.p21 is a cyclin-dependent kinase inhibitor that regulates the cell cycle, thus it acts as an inhibitor in cell proliferation. PURPOSE This study was aimed to evaluate and c...

oral lichen planus (olp) is classified as a potential malignant disorder, and epidermal growth factor (egf) may play a key role in cancer development. the aim of this study was to compare serum and saliva egf among patients with olp and oral squamous cell carcinoma (oscc). a cross-sectional study was performed on 27 patients with olp (10 reticular and 17 atrophic-erosive forms), 27 patients wit...

background: lichen planus is a common mucocutaneous disease with unknown etiology. immunodeficiency is a known predisposing factor to this disease. oral candidiasis which is an opportunistic fungal infection, commonly affects healthy and immune-compromised patients. candida has different species bearing different treatments. in this study, researchers aimed to detect the frequency and colonizat...

conclusions this study showed that topical glycyrrhiza glabra appeared to be a promising alternative in the treatment of olp. further studies should be conducted to assess the long-term effects of glycyrrhiza glabra. objectives the aim of this study was to compare the efficacy and safety of 1% glycyrrhiza glabra in orabase with 0.1% triamcinolone acetonide paste in treating oral lichen planus (...