The potential for malignant transformation of oral lichen planus is still controversial. The expression of proteins related to cell proliferation and apoptosis in oral lichen planus and epithelial dysplasia was analyzed to evaluate the true potential for malignant transformation of this disease. Twenty-four cases of each lesion were subjected to the streptoavidin-biotin technique for identifyin...

it has been argued that oral lichen planus (olp) may increase the risk of oral cancer. patients with olp may be at an increased risk for developing of oscc (oral squamous cell carcinoma). here, the author reports a case of olp initially presenting with a clearly benign olp lesion that transformed into oscc over a course of 18 months. this report may provide a clear evidence for olp lesion as a ...

OBJECTIVES The objective of this study was to identify salivary and serum concentrations of interleukin (IL)-8, IL-6, and tumor necrosis factor alpha (TNF-α) in patients with oral lichen planus, oral leukoplakia, oral submucous fibrosis, and healthy controls. MATERIALS AND METHODS Patients selected included 54 oral lichen planus (41 to 65 years), 50 oral leukoplakia (42 to 65 years), 51 oral ...

Lichen planus is an inflammatory, mucocutaneous disease that in addition to the skin involves oral mucosa in about 60-70 % of cases. In recent years, several reports have supposed a relationship between oral lichen planus (OLP) and chronic liver disease, especially hepatitis C (HCV). Here we present an extensive review of the literature in English that examines the association between HCV and OLP.

1. Gutte R, Khopkar U. Predominant palmoplantar lichen planus: A diagnostic challenge. Indian J Dermatol 2014;59:343‐7. 2. Pavitran K, Karunakaram M, Palit A, Raghunatha S. On disorders of keratinisation. In: Valia RG, Valia AR, editors. IADVL Textbook of Dermatology. 3rd ed. Mumbai, India: Bhalani Publishers; 2008. p. 995‐1069. 3. Gutte RM. Unilateral acrosyringeal lichen planus of palm. India...

Lichen planus is a benign disorder characterized by an itchy, noninfectious skin rash. Though lichen planus is a common papulosquamous disorder affecting about 1-2% of the population, neoplastic transformation of cutaneous lichen planus lesions occurs very rarely and should be borne in mind while treating nonhealing longstanding lesions of lichen planus. Studies suggest an estimated 0.3-3% risk...

background and aims. the clinical management of oral lichen planus poses considerable difficulties to the clinician. in recent years, researchers have focused on the presence of pathogenic microorganisms such as candida albicans in the patients with refractory lichen planus. the aim of the present study was to investigate the prevalence of candida species in the erosive oral lichen planus lesio...

CLP: cutaneous lichen planus DIF: direct immunofluorescence dsDNA: double-stranded DNA SLE: systemic lupus erythematosus OLP: oral lichen planus INTRODUCTION Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease that can involve oral mucosal membranes in up to 45% of patients. Oral presentation is commonly described as erythema involving multiple oral sites. Oral ulceration is ...

Oral lichen planus (OLP) is a common inflammatory disease with unknown etiology. Depression, stress and anxiety are psychological factors that their influence on the expression of lichen planus by affecting the immune system's function has been confirmed. There is a probable relationship between anger and OLP expression. Therefore, the present study aimed to evaluate the association of "anger" ...

lichen planus (lp) is a chronic inflammatory disease of probable immune-based etiology. the pathogenesis of lp is unclear, but apoptotic changes in epidermal (epithelial) cells have been reported. destruction of the basal cell layer is observed and many changes in cell proliferation, cell repair and cell death occur in the injured mucosal epithelium. the aim of this study was to evaluate and co...