Pemphigus is a blister forming disease of both mucosa and skin autoimmune origin. Most commonly seen in old age individuals oral lesions precede the most cases. This report unique case pemphigus vulgaris an elderly male patient where started initially followed by lesions. It was provisionally diagnosed our medicine specialists on very first visit confirmed after biopsy. The treated successfully...

While chronic wasting disease (CWD) prion transmission, entry, and trafficking remain incompletely elucidated, natural exposure of the oral and/or nasal mucous membranes seems certain. Cervids commonly sustain minor lesions on oral mucous membranes that could have an impact on susceptibility to prion infection. To explore this potential cofactor, we studied cohorts of cervid PrP transgenic mice...

tuberculosis is a major cause of morbidity and mortality worldwide. it is a chronic granulomatous disease that can affect any part of the body, including the oral cavity. oral lesions of tuberculosis, though uncommon, are seen in both the primary and secondary stages of the disease. this article presents a case of tuberculosis of the buccal mucosa, manifesting as non-healing, non-painful ulcer....

A burning sensation of the oral mucosa without any obvious lesions is a defining feature mouth syndrome (BMS), chronic and untreatable orofacial pain syndrome. Women in their later years life who are experiencing hormonal shifts or psychological issues most affected by this ailment. BMS patients also complains mucosa, taste perception changes dry with sensation. Even though exact cause unknown,...

Focal epithelial hyperplasia (FEH) or Heck’s disease is a rare viral infection of the oral mucosa caused by human papilloma virus especially subtypes 13 or 32. The frequency of this disease varies widely from one geographic region and ethnic groups to another. This paper reports an Iranian case of extensive focal epithelial hyperplasia. A 35-year-old man with FEH is described, in whom the lesio...

primary oral melanoma is a rare neoplasm of melanocytic origin, accounting for 0.5% of all oral malignancies. the “chameleonic” presentation of a mainly asymptomatic condition, rarity of this lesion, poor prognosis, and the necessity of a highly specialized treatment are factors that should be seriously considered by the involved health provider. here is a case report presenting a malignant mel...

BACKGROUND Protective athletic mouthguards (PAMs) have been worn in competitive sports for more than 100 years. Today, participants in contact and noncontact sports wear PAMs. HYPOTHESIS Wearing a PAM produces oral injury. STUDY TYPE Case series. STUDY DESIGN AND METHODS Sixty-two Division I football players voluntarily participated in the study. Before the beginning of the season, each p...

BACKGROUND AND OBJECTIVES Autofluorescence and diffuse reflectance spectroscopy have been used separately and combined for tissue diagnostics. Previously, we assessed the value of autofluorescence spectroscopy for the classification of oral (pre-)malignancies. In the present study, we want to determine the contributions of diffuse reflectance and autofluorescence spectroscopy to diagnostic perf...

background and aims. many oral squamous cell carcinomas develop from potentially malignant disorders (pmds) which include a variety of lesions and conditions characterized by an increased risk for malignant transformation. this study evaluated the quantitative expression of egfr in normal oral mucosa, oral leukoplakia and oral submucous fibrosis to predict the malignant risk in compliance with ...

The purpose of this study is to demonstrate that the GOCCLES® medical device allows proper autofluorescence examination of the oral mucosa in a dental care setting. This is a non-randomised multicentre clinical trial on consecutive patients at risk for oral cancer. Patients underwent a classical naked eye inspection of the oral cavity followed by autofluorescence examination wearing the GOCCLES...