nystatin oral suspension is a safe firstline therapy; fluconazole is more effective (strength of recommendation [sor]: B, 1 small randomized controlled trial [rCT]) but has not been approved by the Food and Drug Administration (FDA) for use in immunocompetent infants. Miconazole oral gel is also more effective than nystatin suspension, but is not commercially available in the united states (sor...

Candida vaginitis Other than the dermatophytic mycoses, Candida vaginitis is the most common fungal disease in the United Kingdom, described by Morton and Rashid (1977) as a near epidemic. Almost all the known facts about it are enumerative or descriptive and little is known of the factors affecting the pathogenesis, recrudescence, or recurrence of the mycosis. The facts do not disclose the psy...

On examination, he had white adherent plaques of thrush and angular cheilitis [Figures 1A and 1B]. His nails were markedly thickened, fragmented, and discolored [Figure 2A]. He also had skin lesions characterized by erythematous, hyperkeratotic, serpiginous plaques over arms [Figure 2B] and scarring alopecia. His investigations revealed hemoglobin of 14.4 gm%, total WBC count 7800cells/mm and d...

F infect ions have been mentioned in ancient scriptures of Hinduism e.g. Atharva Veda and also in the writings of Hippocrates who described mouths affected with aphthous ulcerations which is now recognized as oral thrush. The earliest recognition of fungi as a cause of disease came from discovery of infection in silk worms by “budding globules of vegetable kingdom capable of reproducing themsel...

Yeast, along with a mix of healthy bacteria, is something that?s normally found in the body, including the vaginal canal. When the balance of these are thrown off, yeast can sometimes grow out of hand and result in an infection. Based on some of the strategies you?ve mentioned, it seems you might referring to vaginal yeast infections specifically. However, you might also be interested to know t...

A baby boy, aged 14 days, presented with a temperature of 38.2°C (100.8°F), a generalized maculopapular rash, and purulent otorrhea. He was treated with oral amoxicillin for 10 days. At age 25 days, he again presented—this time with erythema and edema of the umbilicus, thrush, and fever of 24 hours' duration. The cord stump had dried and fallen off 2 days earlier. (The umbilical stump had been ...

A 12-year-old adolescent girl with intractable pneumonia and desaturation was sent to our hospital. An immunocompromised state was highly suspected because of an oral thrush persisting for a year and pneumonia of unusual severity. Laboratory tests confirmed she had human immunodeficiency virus (HIV) infection and full-blown AIDS. She lived with her adopted parents and reported no history of sex...

A study was conducted among patients attending a public health centre in Nairobi, Kenya in order to (a) verify the prevalence of HIV, (b) identify clinical risk factors associated with HIV and (c) determine clinical markers for clinical screening of HIV infection at the health centre level. Of 304 individuals involved in the study,107(35%) were HIV positive. A clinical screening algorithm based...