Behçet disease is relatively rare in pediatric age group. And the bowel involvement is seen in only a small portion of Behçet disease. However, once the bowel is involved it is potentially life threatening event. We report a 15 year old boy with intestinal Behçet's disease who had a history of recurrent oral and genital ulcers for several years. He underwent right hemicolectomy under the impres...

Mucormycosis, is an emerging fungal infection in immunocompromised and diabetic individuals, usually affects rhino-orbito-cerebral, cutaneous and pulmonary regions. But mucormycosis in immunocompetent environment is rare and occurrence of gastric mucormycosis is unusual. We report a case of 19 year old female, with no pre-existing co-morbidities, presented with fever, dysentery, vomiting, and m...

Upper gastrointestinal bleeding secondary to ulcer disease is common and results in substantial patient morbidity and medical expense. After initial resuscitation to stabilize the patient, carefully performed endoscopy provides an accurate diagnosis and identifies high-risk ulcer patients who are likely to rebleed with medical therapy alone and will benefit most from endoscopic hemostasis. For ...

Eosinophilic ulcer of the oral mucosa is a benign lesion of unclear pathogenesis mostly affecting the tongue. It has been suggested to represent a reactive pattern to several stimuli. We report on a 12-year-old boy who presented with a painless infiltrating ulcer on the gingiva of the lower jaw, which was covered by necrotic yellowish slough. There were no pathologic features of the jawbones or...

Objective: To evaluate the relationship between topically applied non-steroidal antiinflammatory drugs and upper gastro-intestinal bleeding and perforation. Study population: The population of 319,465 people who were resident in Tayside and were registered with a Tayside GP between January 1989 and October 1994. A recordlinkage database containing all hospital event and dispensed drug data betw...

BACKGROUND Bael (Aegle marmelos (L.) Corr.) has been widely used in indigenous systems of Indian medicine to exploit its medicinal properties including astringent, antidiarrheal, antidysenteric, demulcent, antipyretic, antiulcer, anti-inflammatory and anti cancer activities. The present study aims to evaluate the antioxidative and antiulcer effect of methanolic extract of unripe fruit of Aegle ...

BACKGROUND To study the effect (s) of recombinant human Epidermal Growth Factor (rhEGF) on naproxen induced gastric ulcer in Wistar NIN rats. METHODS Male Wistar NIN rats were randomly divided into six experimental groups: Group I - Control, Group II - Naproxen treated, Group III - Naproxen with rhEGF/7 days, Group IV - Naproxen without rhEGF/7 days, Group V - Naproxen with rhEGF/14 days, and...

Helicobacter pylori infection, excessive consumption of alcohol and the prolonged use of nonsteroidal anti-inflammatory drugs (NSAIDS) are the major factors that cause peptic ulcer. Previous studies from our lab revealed the potency of the ethanol extract of the plant, Cardiospermum halicacabum Linn. against ethanol induced gastric ulcerogenesis in rats. The present study intended to compare th...