A DISCUSSION OF THE HEMODYNAMICS of any circulation, and that of the pulmonary circulation in particular, must be concerned with three factors: (1) the flow through the circulation, which in the case of the lung is also the cardiac output; (2) the resistance to flow through the vas-cular bed, which is primarily a function of the number and diameter of resistance vessels , and to a lesser degree...

The molecular mechanisms underlying endotoxin-induced insulin resistance remain unclear. Endotoxin or lipopolysaccharide (LPS) injection is a potent stimulator of inducible nitric oxide synthase (iNOS). This study in rats, using the specific iNOS inhibitor aminoguanidine, investigated the role of iNOS in endotoxin-induced hyperglycemia and insulin resistance. LPS injection led to hyperglycemia,...

Decreased vascular resistance and vasoconstrictor response during pregnancy enables an increase in cardiac output and regional blood flow to the uterine circulation. We sought to determine whether inhibition of vascular smooth muscle ATP-sensitive potassium (K+ATP) channel activity during pregnancy increased systemic and/or regional vascular resistance and resistance response to ANG II. A total...

Chronic intrarenal infusion of angiotensin II (0.5 ng ⋅ kg-1 ⋅ min-1) in dogs increases arterial pressure. In the present study we determined whether this was associated with changes in cardiac output or in total peripheral resistance. Mean arterial pressure did not change initially but was significantly increased over days 14- 28 of the infusion period (+6 ± 2 mmHg), as was total peripheral re...

The solar photovoltaic (PV) systems are facing serious problems due to unavoidable losses in their system, leads to more devation of output power from the input power level. This effect is known as a mismatch effect and is available in PV systems. Many losses are encountered in PV system and it is difficult to minimize such losses. In this paper, the influence of thermal effect on the solar PV ...

OBJECTIVE To investigate the central and peripheral haemodynamic response to dobutamine stress testing in women with suspected ischaemic heart disease and to seek an explanation for the hypotension phenomenon. DESIGN 18 women aged 54-73 years were investigated with Doppler echocardiography and venous occlusion plethysmography during intravenous infusion of dobutamine 5-10 d after an episode o...

The output voltage is a key parameter to quantify the performance of piezoelectric devices, particularly for energy harvesters and sensors. Our recent work (Su et al., 2015) reported that the measured output voltage depends on the inner resistance of voltmeter used. It is contrary to the established concept that the measured results should be independent of the instruments used. Similar measure...