thyroid gland dysfunction is associated with disorders of female reproductive functions. the aim of this study was to examine the effects of hyperthyroidism on ovulation rate and peripheral sex steroid levels in prepubertal and adult rats. two groups of female rats aging 30 days (prepubertal rats) and 60 days (adult rats) were made hyperthyroid by oral administration of levothyroxine daily. in ...

Background Premature ovarian failure (POF) is a disorder of multi causal etiology. Autoimmunity has been proposed as a mechanism for some cases of ovarian follicle dysfunction which is evident in POF. The aim of this study was to identify the level of auto-antibodies in POF and familial POF patients. MaterialsAndMethods In this study, auto-antibodies including anti-ovarian antibody (AOA), anti ...

After surgery for gangrenous - perforated appendicitis, miscarriage occurs in 11%, infertility 62% of cases. The aim the study was to develop an algorithm diagnosis and treatment reproductive dysfunction women who underwent common appendicular peritonitis childhood. 154 girls aged 3 15 years were examined. results showed that various pathologies from system (ovarian failure, inflammatory proces...

microRNAs (miRNAs/miRs) belong to a class of small noncoding RNAs that can negatively regulate messenger RNA (mRNA) expression of target genes. miRNAs are involved in multiple aspects of ovarian cancer cell dysfunction and the phenotype of ovarian cancer cells can be modified by targeting miRNA expression. miRNA profiling has detected a number of candidate miRNAs with the potential to regulate ...

The optimal adjuvant endocrine therapy in premenopausal women with early-stage breast cancer is yet to be elucidated. Studies have demonstrated that women who experience cessation of ovarian function after chemotherapy (chemotherapy-induced amenorrhea) may experience improved survival. These findings, however, have not been replicated when pharmacologic or surgical interventions have been used ...

Women's health is an area that is gaining increasing attention with the realization that men's and women's bodies don't just look different-they also react differently to environmental agents. Barbara J. Davis, head of the Female Reproductive Pathology Group and now acting chief of the newly created Laboratory of Women's Health, is leading women's health studies at the NIEHS. Over the course of...

conclusions as vaginismus can affect the stability of marriage, it is necessary to assess sexual dysfunction from all directions, including demographic characteristics and variables that affect the incidence of vaginismus. therefore, based on the data obtained, we can diagnose and properly treat sexual dysfunction, in time, and teach couples how to deal with it. patients and methods this study ...

Polycystic ovarian syndrome (PCOS) is one of the most common endocrine disorders in women with a heterogeneous clinico-pathologic spectrum characterised by varying degrees ovulatory dysfunction and clinical and/ or biochemical features hyperandrogenism. The etiopathogenesis PCOS remains controversial multiple genetic variants environmental factors interacting together to foster development feat...

BACKGROUND Ovarian angiogenesis is a complex process that is regulated by a balance between pro- and anti-angiogenic factors. Physiological processes within the ovary, such as folliculogenesis, ovulation, and luteal formation are dependent upon adequate vascularization and anything that disrupts normal angiogenic processes may result in ovarian dysfunction, and possibly infertility. The objecti...