BACKGROUND Although metastatic disease is the primary cause of death from epithelial ovarian carcinoma, to the authors' knowledge the cellular mechanisms that regulate intraperitoneal metastasis are largely unknown. Metastasizing ovarian carcinoma cells encounter a collagen-rich microenvironment because the submesothelial matrix is comprised mainly of interstitial collagens Types I and III. M...

Ovarian dermoidal cysts are benign lesions arising from germ cells. If they large, can pose a problem of differential diagnosis with the hydatid cyst. Transformation to malignancy is possible. Complications numerous, going as far peritonitis or even fistulization in hollow organ. We present case dermoid cyst ovary 33-year-old parturient twice scarred uterus who was treated surgically and whose ...

Lau et al. authored a valuable article entitled “Impact of ovarian preservation in women with endometrial cancer”. This retrospective cohort study enrolled 529 patients with endometrial cancer between 2000 and 2010. Among these, 17 were in the ovarian preservation group and 517 in the bilateral salpingo-oophorectomy (BSO) group. The authors investigated the impact of ovarian preservation on the...

A simple, rapid PCR assay for the identification of Renibacterium salmoninarum in Atlantic salmon (Salmo salar L.) tissues detected DNA extracted from between 4 and 40 bacterial cells. PCR was at least as sensitive as culture when it was used to identify subclinically infected fish experimentally challenged with R. salmoninarum. However, PCR identified much higher numbers of kidney tissue and o...

  To study viability and activity of isolated common carp, Cyprinus carpio, ovarian follicular cells (granulosa and theca cells), 17- α -Hydroxy progesterone (17 α -OHP) and 17 β -Estradiol (E2) levels were estimated in the culture media of cultivated carp ovarian follicular cells, using radioimmunoassay (RIA). Oocytes were isolated from the ovaries of female carp. Interstitial tissue was manua...

Globally, ovarian cancer (OC) is the leading cause of gynecological cancer-associated deaths. Metastasis, especially multi-organ metastasis, determines the speed of disease progression. A multicenter retrospective study was performed to identify the factors that drive metastasis, from medical records of 534 patients with OC. The average number of target organs per patient was 3.66, indicating m...

Various toxicants, drugs and their metabolites carry potential ovarian toxicity. Ovarian follicles, the functional unit of the ovary, are susceptible to this type of damage at all stages of their development. However, despite of the large scale of potential negative impacts, assays that study ovarian toxicity are limited. Exposure of cultured ovarian follicles to toxicants of interest served as...