The cerebellum is one of the regions that contribute to urinary dysfunction in humans. A 43-year-old woman at age 35 had an acute onset of encephalitis that led to fever, generalized convulsion and coma. Six months after the disease onset, she regained consciousness and developed generalized myoclonus, cerebellar ataxia and overactive bladder, e.g., urinary urgency, daytime urinary frequency, a...

Around 1.5% of adults in Europe and the USA have urge urinary incontinence (involuntary leakage immediately preceded or accompanied by urgency) (Abrams 2003; Irwin 2006). This is usually due to overactive bladder syndrome (defined as urgency, with or without urge incontinence, and usually with frequency and nocturia) (Abrams 2003). The symptoms of an overactive bladder are thought to be due to ...

After lifestyle and behavioral measures to control overactive bladder, the mainstay of pharmacological treatment is the use of antimuscarinic therapy. Overactive bladder predominantly affects older people, who experience the most severe disease, and are also at a greater risk of side effects from antimuscarinic therapy. Thus it is imperative that data are available on the efficacy and tolerabil...

Overactive bladder is a prevalent condition which negatively impacts quality of life and puts a significant economical burden on society. First-line therapy often includes pharmacotherapy with antimuscarinic medications, and numerous research studies have demonstrated that tolterodine extended-release (ER) is an efficacious and tolerable formulation of this class of medication. This review prov...

Anticholinergics are commonly used in primary and secondary care settings for the treatment of overactive bladder syndrome. The number of anticholinergic drugs available on the market is increasing and various studies, both observational and randomized controlled trials, have evaluated effectiveness of the different preparations available. When anticholinergic therapy is prescribed, there is st...

Serge P Marinkovic director of urology and female pelvic medicine and reconstructive surgery , Eric S Rovner professor of urology , Robert M Moldwin associate professor of clinical urology, director of the Interstitial Cystitis Center , Stuart L Stanton professor emeritus of urogynaecology , Lisa M Gillen independent researcher and writer , Christina MMarinkovic clinical director of nursing ser...

OBJECTIVES although efficacious, some patients do not respond optimally to overactive bladder (OAB) treatment. The objective of this study was to identify the reasons why some patients do not respond and to look for reasons for changes in treatment and patient satisfaction with the new treatment. MATERIALS AND METHODS epidemiological, cross-sectional, non-interventional study to determine the...

We report a rare case of Myasthenia gravis and overactive bladder successfully treated with pretibial nerve stimulation.

Around 1.5% of adults in Europe and the USA have urge urinary incontinence (involuntary leakage immediately preceded or accompanied by urgency) (Abrams 2003; Irwin 2006). This is usually due to overactive bladder syndrome (defined as urgency, with or without urge incontinence, and usually with frequency and nocturia) (Abrams 2003). The symptoms of an overactive bladder are thought to be due to ...

Abstract Aims Sexual dysfunction (SD) is common in female patients with multiple sclerosis (MS) reporting overactive bladder (OAB) symptoms. The aim of the study was to evaluate effects transcutaneous tibial nerve stimulation (TTNS) and pelvic floor muscle training (PFMT) biofeedback on SD MS OAB Methods Patients were allocated receive TTNS or PFMT daily. Overactive symptoms, sexual functions, ...