background: multifactorial regression models are frequently used in medicine to estimate survival rate of patients across risk groups. however, their results are not generalisable, if in the development of models assumptions required are not satisfied.  missing data is a common problem in pathology. the aim of this paper is to address the danger of exclusion of cases with missing data, and to h...

data envelopment analysis (dea) is a non-parametric technique for evaluation of relative efficiency of decision making units described by multiple inputs and outputs. it is based on solving linear programming problems. since 1978 when basic dea model was introduced many its modifications were formulated. among them are two or multi-stage models with serial or parallel structure often called net...

background: breast cancer arising in young patients (≤ 40 years) is being considered as a distinct clinical entity with more aggressive tumor features and poorer survival. our aim was to assess the impact of age on survival among a large group of iranian women diagnosed with breast cancer. methods: in a cross-sectional study, demographic and clinicopathological characteristics of patients with ...

Firstly, decomposition of multifunctional embedded systems into subsystems implies a long list of relevant criteria to be taken into consideration. Secondly, reuse of such subsystems is already done in practice but is often just performed for code or lacks a systematic approach. In this paper, we describe a method for defining and outlining subsystems from the overall system requirements and sp...

This study examines the extent to which the major dimensions of the cranial base (maximum length, maximum breadth, and flexion) interact with brain volume to influence major proportions of the neurocranium and face. A model is presented for developmental interactions that occur during ontogeny between the brain and the cranial base and neurocranium, and between the neurobasicranial complex (NBC...

The implementation of software has benefited from the advanced concern separation mechanisms the Aspect-Oriented paradigm enables, allowing for the textual localization of scattered and tangled concerns in source code. In this deliverable, we summarize an approach that shows how AOP can be made beneficial to activities taking place earlier in the software development life cycle. Specifically, w...

Discourse relations can be categorized as continuous or discontinuous in the hypothesis of continuity (Murray, 1997), with continuous relations expressing normal succession of events in discourse such as temporal, spatial or causal. Asr and Demberg (2013) propose a markedness measure to test the prediction that discontinuous relations may have more unambiguous connectives, but restrict the mark...

We discuss the problem of theoretical uncertainties in the combination of observables related to the CKM matrix elements and propose a statistically sensible method for combining them. The overall fit is performed on present data, and constraints on the matrix elements are presented as well as on fBd √ BBd. We then explore the implications of recent measurements and developments: J/ψK S CP asym...

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When predicting the overall loudness of time-varying sounds, it is necessary to use a function which calculates an overall value based on instantaneous loudness. Although N5 and LL(P) correlate for many sounds, their concepts are rather different. N5 is the loudness which is exceeded in five percent of the time, thus it is an ordinal value. LL(P) is the energetic mean of all instantaneous loudn...