abstract please cite this article as: goudarzi h, douraghi m, ghalavand z, goudarzi m. assessment of antibiotic resistance pattern in acinetobacter baumannii carrying bla oxa type genes isolated from hospitalized patients. novel biomed 2013;1(2):54-61. introduction: acinetobacter baumannii is a gram-negative coccobacillus and one of the most opportunistic pathogens responsible for serious infec...

A three-component coupling reaction of ortho-phthalaldehyde, 9,10-dihydro-9-oxa-10-phosphaphenanthrene 10-oxide, and various primary amines readily afforded novel phosphorus-substituted stable isoindoles in good to excellent yields. The importance the reversible ring-opening 10-oxide by methanolysis became apparent.

BACKGROUND Carbapenem resistant Acinetobacter baumannii is an important nosocomial pathogen associated with a variety of infections. OBJECTIVES The current study aimed to characterize the antimicrobial susceptibility, analyze the prevalence of oxacillinase and metallo-β-lactamase (MBL) genes and molecular typing of clinical isolates of A. baumannii. MATERIALS AND METHODS A total of 124 non-...

Due to an increase in serious infections and a lack of efficient therapies, Klebsiella pneumoniae has recently gained more recognition. The production carbapenemases is one the most common strategies by which K. acquire resistance carbapenems considered last resort antibiotics. Previously collected isolates from different clinical settings on basis their genetic profile, mainly absence presence...

a facile and efficient protocol for the synthesis of 1,8-dioxo-octahydroxanthenes has been developed by one-pot knoevenagel condensation, michael addition and cyclodehydration reaction of dimedone (active methylene carbonyl compound) with aromatic aldehydes in the presence of iron (iii) sulfate hydrate as a solid acidic catalyst under solvent-free conditions. various aromatic aldehydes were uti...

Efficient and one-pot synthesis of 1,8-dioxo-octahydroxanthenes was described by Knoevenagel condensation, Michael addition and cyclodehydration of dimedone. This reaction was carried out through condensation of dimedone and various aromatic aldehydes in the presence of task-specific Brønsted acidic ionic liquid under solvent free conditions. The catalyst could be recycled five times without si...