INTRODUCTION Permanent pacemaker implantation is available in Nigeria. There is however no national registry or framework for pacemaker data collection. A pacemaker database has been developed in our institution and the results are analyzed in this study. METHODS The study period was between January 2008 and December 2012. Patient data was extracted from a prospectively maintained database wh...

OBJECTIVES We evaluated the incidence, predictors, and treatment of pacemaker syndrome in patients with sinus node dysfunction treated with ventricular-based (VVIR) pacing in the Mode Selection Trial (MOST). BACKGROUND Pacemaker syndrome, or intolerance to VVIR pacing, consists of cardiovascular signs and symptoms induced by VVIR pacing. METHODS The definition of pacemaker syndrome required...

AIM To investigate the effects of a water extract of Hwangryunhaedok-tang (HHTE) on the pacemaker potentials of mouse interstitial cells of Cajal (ICCs). METHODS We dissociated ICCs from small intestines and cultured. ICCs were immunologically identified using an anti-c-kit antibody. We used the whole-cell patch-clamp configuration to record the pacemaker potentials generated by cultured ICCs...

Chest wall electrical stimuli, too weak to affect the heart, act as electrical signals to an implanted ventricular-inhibited (QRS blocking) demand pacemaker which interprets them as originating from the heart and consequently responds according to its specifications. Rapid external stimulation permits diagnostic interpretation of the spontaneous electrocardiogram by completely inactivating the ...

A rule-based expert system has been proposed that will assist clinicians in the often difficult task of analyzing multi-channel pacemaker electrocardiograms (ECGs). Analysis of the pacemaker ECGs is important to the follow-up evaluation of patients with implanted pacemakers. Because of the complexity and variability of pacemaker algorithms, diagnosis of pacemaker ECGs is often considerably more...

atopy can be defined as the genetically determined risk to develop allergic disease. avoidance of one specific allergen may decrease the risk for sensitization against this allergen, but it will not affect atopy. our aim was to investigate if exclusive breast-feeding is associated with atopic dermatitis during the first 5 years of life. data on 200 children were taken from parental-administered...

Cultures for Malassezia yeasts were taken from both normal-looking skin and lesional skin in 124 patients with atopic dermatitis, 16 patients with seborrhoeic dermatitis and from normal skin of 31 healthy controls. Positive Malassezia growth was found in fewer patients with atopic dermatitis (56%) than in patients with seborrhoeic dermatitis (88%) or in healthy controls (84%, p<0.01). In the pa...

Runaway pacemaker results from pacemaker malfunction and is characterized by sudden increases in the stimulus rate above the set upper rate limit of the pacemaker. Here we report the case of a patient with wide QRS complex tachycardia who was admitted to the emergency unit and diagnosed with runaway pacemaker.

PURPOSE OF REVIEW To describe recent developments in therapies which target the molecular mechanisms in atopic dermatitis. RECENT FINDINGS Current advances in the understanding of the molecular basis of atopic dermatitis are leading to the stratification of different atopic dermatitis phenotypes. New therapies offer the option to target-specific molecules involved in the pathophysiology of at...

background: cercariae (larva of helminth parasites) are covered by a thick glycocalyx coat, which serves as an osmotic pro­tection during their free existence, and contain carbohydrates conjugated as glycoproteins, glycolipids and mu­co­polysaccharides. although, limited studies have been made on life cycle of cercariae from fresh water snails, however, car­bo­hydrate studies on cercariae have ...