Paecilopeptin, a novel cathepsin S inhibitor, was produced and isolated from the culture supernatant of the fungal strain, Paecilomyces carneus. A spectroscopic analysis revealed the planar structure of paecilopeptin to be acetyl-Leu-Val-CHO. The stereochemistry of the constituent amino acids was analysed by chiral HPLC after oxidation and 6N HCl hydrolysis of paecilopeptin. The total synthesis...

A 61-year-old hypertensive woman on continuous ambulatory peritoneal dialysis (CAPD) with a swan neck Tenckhoff catheter for the past 2 years undergoing four exchanges/day, and on anti-tuberculous treatment presented with poor drainage of the dialysate effluent for 5 days. At presentation, a cheesy material was seen in the catheter with cloudy effluent and poor inflow–outflow. The exit site and...

Paecilomyces lilacinus, an environmental mold found in soil and vegetation, rarely causes human infection. We report the first case of P. lilacinus isolated from a vaginal culture in a patient with vaginitis.

The effect of two fungicides, Caocobre and Ridomil on rhizosphere phenomenon of Cocoa (Theobroma cacao L) seedlings has been studied at different stages of the development of the plant growing in pots. Fungal population in the rhizophere soil was generally higher than in the non-rhizosphere soil. The total number of fungal population in both the rhizosphere and non-rhizosphere was highest on th...

Entomopathogenic fungi are important controllers of pest-insects populations in agricultural production systems and in natural environment. These fungi have enzymatic machinery which involve since the recognition and adherence of spores in their hosts culminating with infection and death of these insects. The main objective of this study was to analyzed extracellular enzyme production of the fu...

BACKGROUND Soil and effluent of lead and zinc industries contain high concentration of cadmium. The present study was conducted to isolate tolerant fungal strains from cadmium -polluted sites in Zanjan province, Iran. METHODS Cadmium tolerance and bioremediation capacity of seven isolates including Aspergilus versicolor, Aspergillus fumigatus, Paecilomyces sp.9, Paecilomyces sp.G, Terichoderm...