Fatty acids of the phospholipid fraction of bronchoalveolar lavage fluid from patients with bacterial pneumonia or with the adult respiratory distress syndrome were chromatographed and the patterns compared with those for a control group. In the control group, palmitic acid (16:0) was the predominant fatty acid, accounting for 58.0% (SD 8.25%) of the total fatty acid, a proportion significantly...

The location of cell proteins with covalently attached lipid was examined in two human squamous-carcinoma cell lines. Cells were labelled with either palmitic acid or myristic acid and disrupted by sonication, followed by differential centrifugation of the cell lysates. SDS/polyacrylamide-gel electrophoresis of the resulting cell fractions indicated that most of the palmitate-labelled proteins ...

The fatty acid composition was evaluated in field grown sesame cultivars (Sesamum indicum L.) at New Developmental Farm Agriculture University, Peshawar, KPK Pakistan during summer 2012. The experiment was laid out in RCBD with split plot arrangement having four replications each. Two sesame cultivars viz., local black and local white were sown at different dates i.e. 20 June, 10 and 30 July, a...

Competition and oxidation of fatty acids spread at the air/water interface were investigated using surface-specific, broad-bandwidth, sum frequency generation spectroscopy. At the air/water interface, a monolayer of oleic acid replaced a monolayer of deuterated palmitic acid at equilibrium spreading pressure. Subsequent oxidation of the oleic acid monolayer with ozone resulted in products more ...

BACKGROUND Type 2 diabetes is associated with increased plasma concentrations of non-esterified fatty acids (NEFAs), which trigger pancreatic β-cell dysfunction and apoptosis. Only long-chain saturated NEFAs induced lipotoxicity in rat insulin-producing cells in in vitro experiments, whereas unsaturated NEFAs were not toxic. Some unsaturated NEFAs even protected against lipotoxicity. In former ...

BACKGROUND The nature of dietary fats affects the postprandial activation of the hemostatic system. OBJECTIVE We investigated whether the ratio of oleic to palmitic acid [and that of monounsaturated to saturated fatty acids (MUFA:SFA)] in the diet affects postprandial concentrations of triacylglycerols, tissue factor (TF), fibrinogen, tissue-type plasminogen activator (t-PA), and plasminogen ...

OBJECTIVE Macrophage endothelial lipase (EL) is associated with increased atherosclerosis and inflammation. Because of their anti-inflammatory properties we hypothesized that n-3 fatty acids, in contrast to saturated fatty acids, would lower macrophages and arterial EL and inflammatory markers. METHODS AND RESULTS Murine J774 and peritoneal macrophages were incubated with eicosapentaenoic aci...

It is generally recognized that the pathways of fatty acid breakdown and of glucose catabolism (Embden-Meyerhof scheme) are confluent at the level of the 2-carbon fragment (acetyl-S-CoA). Nevertheless, several observations suggest an interplay between the metabolism of carbohydrate and that of fatty acids at a higher level: (a) Rats forcibly fed carbohydrate, as opposed to those fasted, exhibit...

Recently, Temme et al (1) reported the effects of feeding diets enriched in lauric, palmitic, or olcic acid on plasma lipids in 32 normocholcstcrolemic men and women. The results showed that lauric acid was more hypercholesterolemic than palmitic acid and both were hypercholesterotemic compared with olcic acid. The subjects consumed solid food diets and the authors managed an 8% of energy excha...