97 Vogt-Koyanagi-Harada syndrome is generally a rare multisystemic autoimmune disorder involving with pigmented structures, such as the eye, meninges, inner ear and skin. The syndrome typically presents as an episode of bilateral panuveitis after prodromal symptoms similar to aseptic meningitis. Auditory disturbances include tinnitus, hearing loss and vertigo. We report the case of a 74-year-ol...

Vogt-Koyanagi-Harada (VKH) syndrome is a bilateral granulomatous panuveitis with central nervous system, auditory, and integumentary manifestations. Typically, ocular involvement is a panuveitis associated with choroidal lesions, exudative retinal detachments, and optic nerve inflammation. Treatment requires high-dose systemic corticosteroids, usually for a prolonged period, often with addition...

PURPOSE This study aims to determine uveitis specialists' practice patterns, preferences, and perceptions of corticosteroid-sparing therapies for the initial treatment of chronic noninfectious uveitis. METHODS A survey was distributed to the American Uveitis Society and Proctor email listservs in order to restrict the respondents to specialists who likely have extensive experience in the use ...

BACKGROUND We report a case of severe bilateral panuveitis during melanoma therapy with a combination of Dabrafenib, a B-raf (BRAF) inhibitor, and Trametinib, a mitogen/extracellular signal-regulated kinase (MEK) inhibitor. Both of these drugs are effectors in the mitogen-activated protein kinase (MAPK) pathway, which plays an important role in the physiopathology of melanoma. Dabrafenib and Tr...

PURPOSE Uveitis associated with psoriasis vulgaris is usually seen as an anterior segment inflammation, and it is very rare that the inflammation extends to the posterior segment. We herein report a case of severe panuveitis associated with psoriasis vulgaris presenting as retinal neovascularization, leading to vitreous hemorrhages that were successfully treated with infliximab (IFX). CASE RE...

BACKGROUND/AIM Epidemiological studies of blindness in a working age population require a precise definition of the true connection of uveitis and visual damage. Since most patients with more severe types of uveitis are hospitalized in tertiary referral uveitis service, our aim was to determine whether age, sex and age of onset of uveitis, as well as duration of visual loss and its causes influ...