The extent to which that hospital, under direction of Dr. L. Guttmann, has been responsible for progress in the treatmen'1 paraplegia is well known throughout the world. During the First World War. 80% of the victims of spinal injury died in the first few months. Now, the death'r:j, is less than 8%, and over 85% of the patients treated at Stoke Mandeville are gaiii^. employed, lead a full and i...

Between 1944 and 1984 20 patients were admitted to a spinal injuries centre with a diagnosis of traumatic paraplegia. They subsequently walked out and the diagnosis was revised to hysterical paraplegia. A further 23 patients with incomplete traumatic injuries, who also walked from the centre, have been compared with them as controls. The features that enabled a diagnosis of hysterical paraplegi...

Post-thoracotomy paraplegia after thoracic surgery is a catastrophic complication. We present one such case following resection of a benign posterior mediastinal tumour. Paraplegia was caused by spinal cord compression due to epidural migration of haemostatic agent i.e. bone wax through the spinal canal. Timely intervention leads to the successful outcome.

Paraplegia secondary to spinal cord infarction is a recognized complication of open thoracic and thoracoabdominal aortic aneurysm (TAA) repair. TAA is serious and unpredictable condition. Therefore, aortic repair requires thorough information on managing the potential complications will facilitate improve control the problem. We report the symptoms and management of paraplegia in a patient who ...

Hereditary spastic paraplegia is a group of clinically and genetically heterogeneous neurodegenerative disorders, often characterized by weakness and spasticity in the lower limbs. In our study, we describe a spastic paraplegia type 7 patient with an expanded phenotype who was diagnosed after the discovery of pathogenic variants in SPG7.

Bektaş G, Yeşil G, Yıldız EP, Aydınlı N, Çalışkan M, Özmen M. Hereditary spastic paraplegia type 35 caused by a novel FA2H mutation. Turk J Pediatr 2017; 59: 329-334. Hereditary spastic paraplegia type 35 (SPG35) is a rare disorder characterized by progressive spasticity. Mutations in the fatty acid 2-hydroxylase (FA2H) gene in different loci are responsible for phenotypic variability. We aimed...

The hereditary spastic paraplegias (HSP) are a large group of inherited neurologic disorders that share the primary symptom difficulty in walking due to weakness and spasticity lower limbs. Spastic paraplegia-48 (SPG48) is an autosomal recessive disorder characterized by limbs resulting gait difficulties. Biallelic mutations AP5Z1 known cause this complex form paraplegia referred as SPG48 (MIM#...

For many years it has been recognized that changes may take place in the skeletal bony and soft tissues in paraplegic patients. Madame Dejerine and her co-workers described such changes in 1918 and 1919 (Dejerine and Ceillier, 1918; D1jerine, Ceillier and Dejerine, 1919). War injuries, road and industrial accidents have been responsible for an increased number of paraplegic patients, many of wh...

Aspergillus infection of the spine is rare; for it to lead to paraplegia is still more rare. When this does occur it is usually treated by decompression and antifungal agents, but the results have usually been poor. We report two cases of successful conservative treatment of Aspergillus paraplegia in patients with chronic granulomatous disease.