Parathyroid carcinoma is a rare etiology of primary hyperparathyroidism responsible for 0.4 to 5.2% of all primary hyperparathyroidism cases. The overt hyperparathyroid bone or renal disease with palpable neck mass, as well as severe hypercalcemia with extremely high parathyroid hormone, are clinical parameters raising the suspicionforparathyroid carcinoma. However a definite diagnosis can be c...

BACKGROUND AND OBJECTIVES Total thyroidectomy is indicated in most cases with postcricoid carcinoma, circumferential hypopharyngeal carcinoma and in advanced laryngeal carcinoma. Persistent hypoparathyroidism is a frequent complication after total thyroidectomy which is difficult to manage unlike hypothyroidism. This study was to assess the feasibility of parathyroid gland autotranplantation af...

PURPOSE Although several reports have been published regarding the coexistence of hyperparathyroidism and papillary thyroid carcinomas, concurrence of parathyroid adenoma and papillary thyroid carcinoma is extremely rare. The aim of this study was to describe experiences with concurrent parathyroid adenoma and papillary thyroid carcinoma. METHODS Seven patients with concurrent parathyroid ade...

introduction: the purpose of this study is to assess the integrated role of scintigraphy by tc99m mibi in diagnosis of parathyroid adenoma and its impacts on the myocardium, and to evaluate whether myocardium perfusion gated spect study could be a complementary routine workup for patient with positive parathyroid adenoma on tc99m mibi parathyroid scan. methods: rest myocardium perfusion gated s...

objective(s): in this study, we aimed to analyze the relationship between the diagnostic ability of fused single photon emission computed tomography/computed tomography (spect/ct) images in localization of parathyroid lesions and the size of adenomas or hyperplastic glands. methods: five patients with primary hyperparathyroidism (phpt) and 4 patients with secondary hyperparathyroidism (shpt) we...

Subcutaneous Parathyroid Hormone in ADH1 In this letter, the investigators report that continuous subcutaneous infusion of parathyroid hormone (1-34) six patients who were between ages 5 ...

Calcium homeostasis is a tightly regulated process involving the co-ordinated efforts of the skeleton, kidney, parathyroid glands and intestine. Neoplasms can alter this homeostasis indirectly through the production of endocrine factors resulting in humoral hypercalcaemia of malignancy. Relatively common with breast and lung cancer, this paraneoplastic condition is most often due to tumour prod...

Immunohistochemical staining for parathyroid hormone-related protein was performed in 27 tumours from 19 normocalcaemic and eight hypercalcaemic patients with cancer. All the tumours from hypercalcaemic patients stained positively for the protein, as did 17 tumours from normocalcaemic patients. Only hypercalcaemic patients had biochemical evidence of increased bone resorption and abnormalities ...

BACKGROUND Therapy-refractory persistent hypoparathyroidism after extensive neck surgery is a rare but severe complication. Parathyroid allotransplantation may represent a definitive treatment option. CASE PRESENTATION A 32-year old female was referred to our hospital with intractable persistent hypocalcemia after neck surgery for papillary thyroid cancer. Despite optimal medical treatment in...

We present a case report of a parathyroid adenoma, which presented as a giant cystic neck mass while providing thorough reviews of the pathophysiology of parathyroid adenomas and the differential diagnosis for large, cystic neck masses in adults. A 72 year old female presented to a tertiary academic medical center with a complicated past medical history and was found to have an asymptomatic cen...