The activation of poly (ADP-ribose) synthetase (PARS) subsequent to DNA damage caused by reactive oxygen or nitrogen species has been implicated in several pathophysiological conditions, including ischemia-reperfusion injury and shock. The aim of this study was to investigate whether PARS inhibitors could provide protection against renal ischemia-reperfusion injury in the rat in vivo. Male Wist...


 This work presents the prosodic analysis of Parenthetical Units in spoken Italian and German within theoretical framework Language into Act Theory (L-AcT), which defines such textual units as Parentheses (PARs), i.e. devices used by speaker to add information utterance on a secondary level text. Data were extracted from Minicorpus DB-IPIC resource FOLK corpus. Linguistic content distribu...

Lehetne sok mindenről írni. A ház nyilvánvaló jelenlétéről Budakeszin, a költői illeszkedésről, professzionális léptéktartó formálásról, minden részletében átgondolt és hiteles közelségéről, terek meghittségéről. Mégis, amit leginkább szeretnék megfogalmazni, az az, ami legnehezebb. Mert nincs közelsége, nem kézzelfogható, jelenlévő. Csak érezhető. Valóban, valóságosan lényegileg.

Parametric modelling software is being employed in architectural design exploration with increasing frequency. Examples of systems used in architectural design include Generative Components (Bentley Systems), Grasshopper (Robert NcNeel), Digital Project (Gehry Technologies Dassault Systemes) and others. All of these systems are basically geometry modellers and do not provide quantitative inform...

In this paper, we demonstrate the prototype of a modelling tool that applies graph-based rules for identifying problems in business process models. The advantages of our approach are twofold. Firstly, it is not necessary to compute the complete state space of the model in order to find errors. Secondly, our technique can even be applied to incomplete business process models. Thus, the modeller ...

purpose: to evaluate the effectiveness of pars plana vitrectomy and posterior hyaloid stripping in decreasing macular thickness and improving vision in diabetic macular edema.          methods: this prospective interventional case series includes 30 eyes of 25 diabetic patients with diabetic macular edema with macular thickness exceeding 170 microns and thickened posterior hyaloid. bcva and mac...

Associations between classifiers are among the most fundamental of UML concepts. However, there is considerable room for disagreement concerning what an association is, semantically. These have implications for the modeller because they can result in serious misunderstandings of static structure diagrams; similarly, they have implications for tool developers. In this paper we describe and class...

Whether a given nonlinear solver can reach a feasible point for a set of nonlinear constraints depends heavily on the initial point provided. We develop a range of computationally cheap constraint consensus algorithms that move from a given initial point to a better final point that is then passed to the nonlinear solver. Empirical tests show that this added step greatly improves the success ra...

This paper is a think piece on variations in the structure of stated preference studies when modelling the joint preferences of interacting agents who have the power to influence the attribute levels on offer. The approach proposed is an extension of standard stated choice methods. Known as ‘stated endogenous attribute level’ (SEAL) analysis, it allows for interactive agents to adjust attribute...

Many model applications suffer from the fact that although it is well known that model application implies different sources of uncertainty there is no objective criterion to decide whether a model is suitable for a particular application or not. This paper introduces a comparative index between the uncertainty of a model and the change effects of scenario calculations which enables the modelle...