نتایج جستجو برای: partial resistance

تعداد نتایج: 599572  

Journal: :The Journal of clinical endocrinology and metabolism 1999
M I New S Nimkarn D D Brandon S Cunningham-Rundles R C Wilson R S Newfield J Vandermeulen N Barron C Russo D L Loriaux B O'Malley

A 14-yr-old native American girl from the Iroquois Nation was referred as a potential patient with the syndrome of apparent mineralocorticoid excess. Instead, her evaluation revealed resistance to glucocorticoids, mineralocorticoids, and androgens, but no resistance to vitamin D or thyroid hormones. She lacked Cushingoid features despite significantly high cortisol levels. Menstruation was regu...

2017
Elisabeth Andre-Garnier Bernard Besse Audrey Rodallec Olivier Ribeyrol Virginie Ferre Caroline Luco Laura Le Guen Nathalie Bourgeois Jérôme Gournay Eric Billaud François Raffi Marianne Coste-Burel Berthe-Marie Imbert-Marcille

The objective was to develop a method of HCV genome sequencing that allowed simultaneous genotyping and NS5A inhibitor resistance profiling. In order to validate the use of a unique RT-PCR for genotypes 1-5, 142 plasma samples from patients infected with HCV were analysed. The NS4B-NS5A partial region was successfully amplified and sequenced in all samples. In parallel, partial NS3 sequences we...

Journal: :Cerebrovascular diseases 2008
Amytis Towfighi Bruce Ovbiagele

BACKGROUND AND PURPOSE Although their primary mechanism of action is blood pressure lowering, emerging data suggest that select angiotensin receptor blockers (ARBs), which partially activate the peroxisome proliferator-activated receptor gamma (PPAR-gamma), may effectively treat insulin resistance and dyslipidemia without the toxicity sometimes associated with full PPAR-gamma agonists. Since up...

Journal: :Diabetes 2004
Stéphane Cook Olivier Hugli Marc Egli Barbara Ménard Sébastien Thalmann Claudio Sartori Christophe Perrin Pascal Nicod Bernard Thorens Peter Vollenweider Urs Scherrer Rémy Burcelin

Nitric oxide (NO) plays a major role in the regulation of cardiovascular and metabolic homeostasis, as evidenced by insulin resistance and arterial hypertension in endothelial NO synthase (eNOS) null mice. Extrapolation of these findings to humans is difficult, however, because eNOS gene deficiency has not been reported. eNOS gene polymorphism and impaired NO synthesis, however, have been repor...

2002
Guo-Liang Wang David J. Mackill

Moroberekan, ajaponica rice cultivar with durable resistance to blast disease in Asia, was crossed to the highly susceptible indica cultivar, C039, and 281 F, recombinant inbred (RI) lines were produced by single seed descent. The population was evaluated for blast resistance in the greenhouse and the field, and was analyzed with 127 restriction fragment length polymorphism (RFLP) markers. Two ...

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