Data have been assembled from the published literature on the water-to-micellar sodium dodecyl sulfate (SDS) partition coefficient data for more than 200 compounds and on the gas-to-micellar SDS partition coefficient data for more than 140 compounds. It is shown that an Abraham solvation equation with only five descriptors can be used to correlate the observed partition coefficient data to with...

OBJECTIVE Differences in contrast agent diffusion reflect changes in composition and structure of articular cartilage. However, in clinical application the contrast agent concentration in the joint capsule varies, which may affect the reliability of contrast enhanced cartilage tomography (CECT). In the present study, effects of concentration of x-ray contrast agents on their diffusion and equil...

Partition coefficients of 51 organic compounds in two ionic liquids (IL), 1-ethyl-3-methylimidazolium dicyanamide and trimethylhexylammonium bis((trifluoromethyl)sulfonyl)amide, were measured using inverse gas chromatography from (322.5 to 352.5) K. These partition coefficients were converted into water-to-IL partition coefficients using the corresponding gas-to-water partition coefficients. Bo...

Occupants of former methamphetamine laboratories, often residences, may experience increased exposure through the accumulation of the methamphetamine in the organic films that coat skin and indoor surfaces. The objectives of this study were to determine equilibrium partition coefficients of vapor-phase methamphetamine with artificial sebum (AS-1), artificial sebum without fatty acids (AS-2), an...

The rat brain capillary permeability coefficient was determined for 27 compounds. The relationship of permeability to octanol/water partition coefficient and molecular weight was found to be predictable for drugs with molecular weights less than 400.

background: the 153sm-[tris(1,10-phenanthroline) samarium(iii)]complex (153sm-pl3) was prepared in view of development of targeting therapeutic compounds for malignancies, and interesting in-vitro anti-tumor activities of lanthanide phenanthroline complexes,. materials and methods: sm-153 chloride was obtained by thermal neutron flux (4 × 1013 n.cm-2.s-1) of enriched 152sm2o3 sample, dissolved ...

A model was developed to simulate the uptake of inhaled vapors in the nasal airway of the Beagle dog during cyclic breathing. Input data to the model were morphological and physiological data for the dog, and physiocochemical data for the vapors. The model simulates the nasal airway as a slit-like duct, where air passes between the two airway walls in an ideal plug flow. The thickness of the wa...