نتایج جستجو برای: pasi
تعداد نتایج: 967 فیلتر نتایج به سال:
BACKGROUND Apremilast, an oral phosphodiesterase 4 inhibitor, has an acceptable safety profile and is effective for treatment of plaque psoriasis and psoriatic arthritis. OBJECTIVES To evaluate the impact of apremilast on health-related quality of life (HRQOL), general functioning and mental health using patient-reported outcome (PRO) assessments among patients with moderate to severe plaque ...
BACKGROUND Psoriasis is an immune-mediated, chronic inflammatory disease affecting multiple aspects of patients' lives. Its epidemiology varies regionally; however, nationwide epidemiologic data on psoriasis depicting profile of Korean patients has not been available to date. OBJECTIVE To understand nationwide epidemiologic characteristics and clinical features of adult patients with psoriasi...
BACKGROUND The combination of seawater baths and narrowband ultraviolet B (NB-UVB) is a known treatment for psoriasis. This study evaluates two treatment regimens that combine bathing in geothermal seawater and NB-UVB therapy in comparison with NB-UVB monotherapy. METHODS Sixty-eight psoriasis patients were randomly assigned to outpatient bathing in geothermal seawater combined with NB-UVB th...
BACKGROUND Compared to conventional therapies, biologics are more effective but expensive in treating psoriasis. OBJECTIVE To evaluate the efficacy and cost-efficacy of biologic therapies for psoriasis. METHODS We conducted a meta-analysis to calculate the efficacy of etanercept, adalimumab, infliximab, and ustekinumab for at least 75% reduction in the Psoriasis Area and Severity Index scor...
There are no direct comparison data between infliximab and entanercept in the treatment of psoriasis. This study was a mult icenter, randomised control trial done in the Netherlands to compare the efficacy, outcome of etanercept vs. infliximab in the management of moderate to severe chronic plaque psoriasis. Patients (age 1875 years old) with Psoriasis Area and Severity Index (PASI) ≥10 and/or ...
The immunopathogenesis of psoriasis has been extensively reviewed in recent literature. Human leukocyte antigen (HLA)-Cw6 has been identified as the major psoriasis susceptibility genetic polymorphism and identifies early-onset (type 1) psoriasis (1). Recently Tala-monti et al. (2) observed that the HLA-Cw6 allele is associated with a faster and better clinical response rate to ustekinumab. Ust...
Interleukin-18 is a cytokine with a possible role in the pathogenesis of psoriasis. We examined subpopulations of peripheral blood lymphocytes and their expression of activation markers and correlated this with plasma levels of IL-18 and clinical disease severity in patients with psoriasis. We included 12 patients with psoriasis who had a PASI score from 15 to 48 and compared them to controls. ...
Background & Objective: Psoriasis is a chronic and relapsing disease with a prevalence of 2%. Since it is a chronic and non-fatal skin disease, its impact on quality of life in patients is underestimated compared to other diseases. This study points out to the importance of the quality of life in these patients and their correlation with disease severity. Materials & Methods: Quality of life...
background: psoriasis is a disease which may have a direct impact on the psychological and social aspects of the patient, particularly due to its visibility. to date, we are unaware of any study showing a relationship between psoriasis and psychological parameters such as psychological vulnerability and coping strategies . objective: the aim of this study was to evaluate the effects of psoriasi...
در بیماری پسوریازیس توسط پردازش تصویر pasi زمینه و هدف: این مطالعه به منظور تعیین پارامتر سطح در استاندارد.روش بررسیو انتخاب یک مقدار آستانه ای توسط کاربر، جهت تفکیک پلا کهای پوستی از تصویر استفاده م یکند: در این مقاله با استفاده از پردازش تصویر یک روش نیمه اتوماتیک کامپیوتری ارائه می شود که پارامتر سطحycbcr از فضای رنگی cr اندازه گیری می کند. این روش از هیستوگرام مربوط به پارامتر pasi را در اس...
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