نتایج جستجو برای: patch density pd
تعداد نتایج: 505774 فیلتر نتایج به سال:
We study density-dependent resource harvest patterns due to Bayesian foraging for different distributions of resources. We first consider a forager with information about the stochastic properties of its environment. In this case we show that when the number of food items per patch follows a distribution from the exponential family, the density dependence is given by the ratio sigma2/μ of th...
Programmed cell death protein 1 (PD-1) and its ligand Programmed death ligand 1 (PD-L1) have gained massive attention in cancer research due to recent availability and their targeted antitumor effects. Their role in prostate cancer is still undetermined. We constructed tissue microarrays from prostatectomy specimens from 535 prostate cancer patients. Following validation of antibodies, immunohi...
Mangrove habitats are under severe land use pressure throughout the world and Australia is no exception. Here we describe the heterogeneity of mangrove habitat and its relationship with mangrove bird diversity. We examined the role of mangrove habitat complexity in determining the richness of avian mangrove dependent species (MDS) and interior species, overall bird species richness and density....
To investigate the prognostic value of PD-L1 expression combined with CD8+ TILs density in patients with resected NSCLC and correlations with clinicopathological features. We retrospectively enrolled 178 patients with resected NSCLC from 2011 to 2015. All surgical primary and 58 matched metastatic lymph node specimens were tested for PD-L1, CD8+ TILs, and oncogenic alterations. PD-L1+ was detec...
The loss of striatal dopamine (DA) in Parkinson's disease (PD) models triggers a cell-type-specific reduction in the density of dendritic spines in D(2) receptor-expressing striatopallidal medium spiny neurons (D(2) MSNs). How the intrinsic properties of MSN dendrites, where the vast majority of DA receptors are found, contribute to this adaptation is not clear. To address this question, two-ph...
Multiplex immunofluorescence tissue imaging allows for the simultaneous analysis of multiple cell types and their spatial interactions is increasingly being used to identify new tissue-based biomarkers immunotherapy. However, identification signatures typically requires a priori selection types, marker expression levels, interactions, which can be challenging as number features quickly increase...
The clinical relevance of tumor-infiltrating lymphocytes (TIL) in breast cancer (BC) has been clearly established by their demonstrated correlation with long-term positive outcomes. Nevertheless, the relationship between protective immunity, observed in some patients, and critical features of the infiltrate remains unresolved. This study examined TIL density, composition and organization togeth...
BACKGROUND Both Parkinson's disease (PD) and multiple system atrophy (MSA) have associated sleep disorders related to the underlying neurodegenerative pathology. Clinically, MSA with predominant parkinsonism (MSA-P) resembles PD in the manifestation of prominent parkinsonism. Whether the amount of rapid eye movement (REM) sleep without atonia could be a potential marker for differentiating MSA-...
BACKGROUND Anti-programmed death-1/programmed death-ligand 1 (PD-1/PD-L1) immunotherapy has been proved to be effective on gastric cancer in ongoing clinical trials. However, the value of PD-L1 in predicting responses of patients with gastric cancer to anti-PD-1/PD-L1 immunotherapy is controversial. Some studies suggested that intra- and inter-tumoral heterogeneity of PD-L1 expression might exp...
Ecosystems are degraded through human activities and a healthy ecosystem sustains the requirements of human and natural environment, as well as the conservation of economic and social values. Various indicators are required to assess the health of ecosystems. This study evaluates the factors affecting the overall ecosystems health including: vigor, structure, and resilience in the Iiril watersh...
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