Thrombotic microangiopathy (TMA) describes a pathological process of microvascular thrombosis, consumptive thrombocytopenia, and microangiopathic hemolytic anemia, leading to end-organ ischemia and infarction, affecting particularly the kidney and brain. TMA is a pathological feature of a number of clinical disorders including thrombotic thrombocytopenic purpura, hemolytic uremic syndrome, and ...

Pathological calcification is becoming recognized as an important feature in the dynamics of a variety of diseases, such as renal stone, atherosclerosis, pulp stones, scleroderma and arthritis, etc. from which millions of human beings suffer in all ages. Nanobacterium sanguineum is the first calcium phosphate mineral containing nanoorganism isolated from human blood that causes pathological dis...

The identification and classification of pathological voice are still a challenging area of research in speech processing. Acoustic features of speech are used mainly to discriminate normal voices from pathological voices. This paper explores and compares various classification models to find the ability of acoustic parameters in differentiating normal voices from pathological voices. An attemp...

statement of the problem removal of impacted third molars is the most common oral surgical procedure. many investigators have questioned the necessity of removal in patients who are free of symptoms or associated pathologies. there are currently no data on the prevalence of impacted teeth and associated pathologies in the hamadani population. purpose the aim of this study was to assess the stat...

Pathology is the study and diagnosis of disease. Due to the nature of job, unhealthy habits and voice abuse, the people are subjected to the risk of voice problems. The diagnosis of vocal and voice disorders should be in the early stage otherwise it causes changes in the normal signal. It is well known that most of vocal fold pathologies cause changes in the acoustic voice signal. Therefore, th...

Two pathologists have independently applied 95 separate pathological criteria to 50 cases of inflammatory large bowel disease firmly diagnosed clinically as 25 cases of Crohn's disease and 25 cases of ulcerative colitis. The observer agreement in the recording of each feature has been calculated and correlations have been made between the pathological features and the final agreed diagnosis in ...

Macrophages are key cellular components of the innate immunity, acting as the main player in the first-line defence against the pathogens and modulating homeostatic and inflammatory responses. Plasticity is a major feature of macrophages resulting in extreme heterogeneity both in normal and in pathological conditions. Macrophages are not homogenous, and they are generally categorized into two b...

Pathological speech usually refers to the condition of speech distortion resulting from atypicalities in voice and/or in the articulatory mechanisms owing to disease, illness or other physical or biological insult to the production system. Although automatic evaluation of speech intelligibility and quality could come in handy in these scenarios to assist experts in diagnosis and treatment desig...

BACKGROUND Risks of perineural invasion (PNI) in T1-2 oral tongue squamous cell carcinoma (SCC) have not been specifically elucidated. METHODS Pathological features, including PNI, were re-reviewed under regular hematoxylin-eosin staining in 190 patients with T1-2 oral tongue SCC. RESULTS Tumor thickness >5 mm, PNI(+), and lymphovascular invasion (+) independently predicted lymph node invol...

Objective: To determine the range and prevalence of pathological conditions and demonstration of significant anatomical structures in the maxillary sinuses using the cone beam computerized tomographic (CBCT) scan. Methodology: Case series of 60 CBCT scans of the maxillae. Results: Forty (67%) of the scans were of female patients while the rest (20, 33%) were of males. Remarkably, the majority o...