PURPOSE This multicenter, randomized, crossover study compared preference, ease of use, acceptability, satisfaction, and safety of repeated subcutaneous (SC) self-administrations with prefilled pens and prefilled syringes delivering methotrexate (MTX), in patients with rheumatoid arthritis (RA). PATIENTS AND METHODS The study (ClinicalTrials.gov number NCT01793259) enrolled 120 patients requi...

In this article, we described a new mobile-Health (mHealth) supported clinical pathway of care for people living with medically stable HIV in terms platform acceptability, usability and technical feasibility. The EmERGE mHealth was codesigned clinicians the community, developed using Scrum agile methodology, integrated hospital information systems validated large prospective cohort study 2251 p...

BACKGROUND Even though Swedish national guidelines for stroke care (SNGSC) have been accessible for nearly a decade access to stroke rehabilitation in out-patient health care vary considerably. In order to aid future interventions studies for implementation of SNGSC, this study assessed the feasibility and acceptability of study procedures including analysis of the context in out-patient health...

BACKGROUND Patient identification within and between health services is an operational challenge in many resource-limited settings. When following HIV risk groups for service provision and in the context of vaccine trials, patient misidentification can harm patient care and bias trial outcomes. Electronic fingerprinting has been proposed to identify patients over time and link patient data betw...

fluorescent monitoring of dna amplification is the basis of real-time pcr. absolute quantification can be achieved using a standard curve method. the standard curve is constructed by amplifying known amounts of standards under identical conditions to that of the samples.the objective of the current study is to propose a mathematical model to assess the acceptability of pcr resulys.four commerci...

BACKGROUND AND OBJECTIVE Shoulder arthroscopic surgeries evolve with intense postoperative pain. Several analgesic techniques have been advocated. The aim of this study was to compare suprascapular and axillary nerve blocks in shoulder arthroscopy using the interscalene approach to brachial plexus blockade. METHODS According to the technique used, sixty-eight patients were allocated into two ...

OBJECTIVES To assess women's preferences for, and the acceptability of, medical abortion and vacuum aspiration in the early first trimester. DESIGN Patient centred, partially randomised trial. Medical abortion was performed with mifepristone 600 mg followed 48 hours later by gemeprost 1 mg vaginal pessary. Vacuum aspiration was performed under general anaesthesia. SETTING Teaching hospital ...

BACKGROUND Patients with chronic obstructive pulmonary disease (COPD) often report inadequate access to comprehensive patient education resources. OBJECTIVE The purpose of this study was to incorporate community-engagement principles within a mixed-method research design to evaluate the usability and acceptability of a self-tailored social media resource center for medically underserved patie...

To the Editor: We read the article published by Jain S et al. entitled ‘Newer Innovations in Treatment of Retracted Nipple’ with interest [1]. We would like to congratulate the authors for taking up such a novel method and doing a commendable job. Treating retracted nipple by vigorous sucking by husband is cheap and simple intervention which can be administered even in primary health care setup...

Introduction The 308 nm excimer laser is a widely used device throughout the field of dermatology for many diseases including psoriasis. Although the laser has demonstrated clinical efficacy, there is a lack of literature outlining the safety, efficacy, and patient acceptability of the excimer laser. Methods A literature search on PubMed was used with combinations of the terms "excimer", "exc...