During organogenesis in all multi-cellular organisms, axial patterning is required to transform a single layer organ primordium into a three-dimensional organ. The Drosophila eye model serves as an excellent model to study axial patterning. Dorso-ventral (DV) axis determination is the first lineage restriction event during axial patterning of the Drosophila eye. The early Drosophila eye primord...

Formation of an anisotropy lattice in Co/ Pt multilayers by direct laser interference patterning" (2006). Roger Kirby Publications. 2. We report on the use of direct laser interference patterning to form an " anisotropy " lattice in Co/ Pt thin film multilayers. Co/ Pt multilayers have been extensively studied and, for the compositions studied here, are characterized by strong perpendicular mag...

BACKGROUND The Drosophila pupal eye has become a popular paradigm for understanding morphogenesis and tissue patterning. Correct rearrangement of cells between ommatidia is required to organize the ommatidial array across the eye field. This requires cell movement, cell death, changes to cell-cell adhesion, signaling and fate specification. METHODOLOGY We describe a method to quantitatively a...

3 5 that enable these complex organisms to regenerate their entire body, including the brain. 3 6 Classical data suggest that they may also be capable of long-term memory. Thus, the planarian 3 7 system may offer the unique opportunity to study brain regeneration and memory in the same 3 8 animal. To establish a system for the investigation of the dynamics of memory in a regenerating 3 9 brain,...

Insulator sequences guide the function of distantly located enhancer elements to the appropriate target genes by blocking inappropriate interactions. In Drosophila, five different insulator binding proteins have been identified, Zw5, BEAF-32, GAGA factor, Su(Hw) and dCTCF. Only dCTCF has a known conserved counterpart in vertebrates. Here we find that the structurally related factors dCTCF and S...

We have previously reported the use of a combination of computational simulations and targeted experiments to build a first generation mathematical model of peppermint (Menthaxpiperita) essential oil biosynthesis. Here, we report on the expansion of this approach to identify the key factors controlling monoterpenoid essential oil biosynthesis under adverse environmental conditions. We also inve...

Cuttlefish are known for their ability to quickly alter their total appearance, or body pattern, to camouflage or to communicate with predators, prey and conspecifics. The body patterns of some species have been extensively documented to gain a better understanding of their behaviors. However, the flamboyant cuttlefish (Metasepia pfefferi) is largely unstudied. Recently, aquarists have been abl...

We propose a novel mechanism to describe E×B flow pattern formation based upon the dynamics of propagation of heat-flux modulations. The E × B flows of interest are staircases, which are quasiregular patterns of strong, localized shear layers and profile corrugations interspersed between regions of avalanching. An analogy of staircase formation to jam formation in traffic flow is used to develo...

A network of three classes of proteins consisting of bHLH and MYB transcription factors, and a WD40 repeat protein, TRANSPARENT TESTA GLABRA1 (TTG1), act in concert to activate trichome initiation and patterning. Using YFP-TTG1 translational fusions, we show that TTG1 is expressed ubiquitously in Arabidopsis leaves and is preferentially localized in the nuclei of trichomes at all developmental ...

We demonstrate that "contact patterning" subtractively patterns a wide range of molecular organic films of nanoscale thickness with nanometer-scale accuracy. In "contact patterning", an elastomeric stamp with raised features is brought into contact with the organic film and subsequently removed, generating patterns by the diffusion of the film molecules into the stamp. The mechanism of material...