BACKGROUND In 1979 approximately 2,000 people were exposed to polychlorinated biphenyls (PCBs) and polychlorinated dibenzofurans (PCDFs) due to ingestion of contaminated cooking oil in Taiwan. Although a previous study has shown delayed developmental milestones and poorer neurocognitive functioning in children born to exposed mothers, it is unclear whether neurocognitive functioning was impaire...

Polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and polychlorinated biphenyls (PCBs) were analyzed in 167 random human milk samples from urban and rural areas in Finland. Dietary habits and background information on each mother and child were gathered by questionnaire. Body mass indexes (BMI) before pregnancy and delivery in the rural area were 5-10% higher tha...

“Kanemi Yusho” was caused by the contamination of heated Polychlororinated Bisphenyls (PCBs) for deodorization in manufacturing process rice bran oil at Kanemi Warehouse Co. Ltd., (Kokura-ward, Kitakyushu, Fukuoka, Japan) 1968.People who ingested contaminated developed skin conditions, such as chloracne, which is characterized black and white pustules, well liver kidney diseases. A total 15,000...

Evaluation of immunoaffinity columns (IACs) for dioxin serum sample clean-up requires a determination of the recovery of various dioxin congeners. We compared the IAC performance of different monoclonal and polyclonal anti-dioxin antibodies, measuring the recovery of congeners of polychlorinated dibenzo-p-dioxins (PCDDs). In addition, we measured the recovery of congeners of the structurally re...

Polychlorinated biphenyl (PCB) poisonings occurred in western Japan, where it is called yusho, in 1968, and in central Taiwan, where it is called yu-cheng, in 1979. The average concentrations of PCBs in the adipose tissue, liver and blood of yusho patients and in the blood of yu-cheng patients were 1.9 ppm, 0.08 ppm, 6.7 ppb and 99 ppb, respectively. Seven PCB congeners, such as 2,4,5,3',4'-pen...

BACKGROUND The University of Michigan Dioxin Exposure Study was undertaken to address concerns that the discharge of polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzo furans (PCDFs) from the Dow Chemical Company in the Midland, Michigan, area had resulted in contamination of soils in the Tittabawassee River floodplain and the city of Midland, leading to an increase in reside...

BACKGROUND Toxicological studies and limited human studies have demonstrated associations between exposure to polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) and polychlorinated biphenyls (PCBs) and adverse developmental and reproductive health effects. Given that children may be particularly susceptible to reproductive and developmental effects of organochlorin...

Temporal trends of polychlorinated dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs) and dioxin-like polychlorinated biphenyls (DL-PCBs) in mothers' milk are still quite rare. Data are particularly scarce when it comes to concentrations from the last decade, 2000 and onwards. The aims of the present study were to assess temporal trends of PCDD, PCDF and DL-PCB in mothers' milk from Stockholm, 19...