نتایج جستجو برای: pediatric hematologic disorders
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BACKGROUND Infants with Down syndrome are at increased risk for hematologic abnormalities, including leukemoid reaction, transient myeloproliferative disorder, and congenital leukemia. The differential diagnosis of a vesiculopustular eruption in an infant with Down syndrome and these hematologic abnormalities is broad and includes benign, self-limited disorders as well as life-threatening infec...
Breast hematoma is common after trauma, surgery, or biopsy. Sometimes there is no history of trauma and hematoma can occur in patients with hematologic diseases or coagulation disorders. Breast hematoma may present mamographically as an ill-defined density or spiculated mass mimicking a carcinoma. In this report, a 48-year old woman who underwent mammography because of a painless palpable node ...
Inflammatory myositis is reported in 4-16% of adult systemic lupus erythematosus (SLE) patients. The aim of this study was to determine the prevalence of myositis in a cohort of pediatric SLE patients in the southeastern United States. A retrospective chart review was performed of 55 SLE patients evaluated by Pediatric Rheumatologists in Alabama since January 1, 2008. Patients were defined as h...
Pathogenesis Multiple myeloma (MM) is a hematologic malignancy involving the pathologic proliferation of terminally differentiated plasma cells. It is the second most common hematologic malignancy behind non-Hodgkin lymphoma, with an annual incidence of 4–7 cases per 100,000 in the United States. Clinical symptoms are due to osteolysis of the bone, suppression of normal hematopoiesis, and the o...
The most widely recognized long-term risk of splenectomy is overwhelming bacterial infection. More recently, thrombosis has become appreciated as another potential complication of the procedure. Because of these long-term risks, the indications for and timing of splenectomy are debated in the medical community. Accordingly, the adverse effects and benefits of splenectomy for hematologic disorde...
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