نتایج جستجو برای: penicillin resistant
تعداد نتایج: 208032 فیلتر نتایج به سال:
The increasing emergence of penicillin-resistant and multidrug-resistant strains of Streptococcus pneumoniae will create a serious therapeutic problem in coming years. Trovafloxacin is a novel naphthyridone quinolone with promising activity against S. pneumoniae, including penicillin-resistant strains (MIC for 90% of the isolates tested, 0.25 microg/ml). We compared its in vivo efficacy with th...
OBJECTIVE We studied the prevalence of nasopharyngeal (NP) carriage, antimicrobial susceptibilities, and serotypes of Streptococcus pneumoniae (SP) in children with sickle cell disease (SCD) in the Mid-South. In addition, we examined risk factors for NP carriage of penicillin-resistant SP (PRSP). STUDY DESIGN Between July 1994 and December 1995, we obtained NP cultures from 312 children with ...
Since their first detection in 1988, penicillin-resistant Streptococcus pneumoniae isolates have rapidly spread in Iceland to account for close to 20% of all pneumococcal disease in that country by 1993. The major component (70%) of the resistant pneumococci identified from 1989 to 1992 was the progeny of a single multidrug-resistant clone (Icelandic clone) with a homogeneous chromosomal macror...
Compared with most penicillin-susceptible isolates of Streptococcus pneumoniae, penicillin-resistant clinical isolate Hun 663 contains mosaic penicillin-binding protein (PBP) genes encoding PBPs with reduced penicillin affinities, anomalous molecular sizes, and also cell walls of unusual chemical composition. Chromosomal DNA prepared from Hun 663 was used to transform susceptible recipient cell...
than imipenem, meropenem and ceftriaxone. Our findings suggest that against these multidrug-resistant pneumococcal isolates, the ranking of in vitro activity based on MIC90 for the b-lactams would be ME1036 (0.12 mg/L) (most active).imipenem (0.5 mg/L). meropenem (1 mg/L).ceftriaxone (1 mg/L).cefotaxime (2 mg/L).penicillin1⁄4cefepime (4 mg/L).amoxicillin (8–16 mg/L).cefuroxime (16 mg/L).ampicil...
The risk of foodborne diseases as well the dissemination antibiotic resistant bacteria increases with consumption street-vended food and beverages. This study investigated prevalence Salmonella spp. Citrobacter in beverages sold Chow Kit, Kuala Lumpur, Malaysia. Kirby-Bauer disk diffusion method was used to identify resistance profile isolates towards 11 selected antibiotics. Six beverage sampl...
A seminested-PCR assay, based on the amplification of the pneumococcal penicillin-binding protein 2B gene (pbp2B), was developed for the detection of penicillin-resistant and -susceptible pneumococci in cerebrospinal fluid (CSF) specimens. Species-specific primers (P5 and P6) which amplified a 682-bp conserved region of the transpeptidase-encoding region of the pbp2B gene were used. Four "resis...
Background. Antimicrobial treatment and chemoprophylaxis of patients and their close contacts is critical to reduce the morbidity and mortality and prevent secondary cases of meningococcal disease. Through the 1990's, the prevalence of antimicrobial resistance to commonly used antimicrobials among Neisseria meningitidis was low in the United States. Susceptibility testing was performed to asce...
The antimicrobial resistance of Streptococcus pneumoniae, or pneumococcus, is a growing global problem. In our study, 3,571 invasive pneumococcal isolates, recovered from blood and cerebrospinal fluid samples from patients in Finland between the years 2002 and 2006, showed an increase in erythromycin nonsusceptibility from 16% to 28% (P < 0.0001) over the 5-year study period, as well as a doubl...
individual approaches to the diagnosis and management of penicillin allergy are practiced by clinicians. this cross-sectional survey of physicians was aimed at exploring their ways of dealing with diagnosis and management of penicillin g allergy. of the 235 respondents, 63% believed patients’ self-reported history of penicillin allergy and avoided using penicillin g; 97% do so for pa...
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