OBJECTIVE To describe recent trends in the incidence of nontraumatic amputations among individuals with and without diabetes and estimate the relative risk of amputations among individuals with diabetes in England. RESEARCH DESIGN AND METHODS We identified all patients aged >16 years who underwent any nontraumatic amputation in England between 2004 and 2008 using national hospital activity da...

There is growing recognition that the complications associated with type 2 diabetes may translate into functional impairment in older people (1). This may reflect a link between the metabolic and mechanical functions of muscle. However, the possibility that the link between glucose tolerance and physical function extends to people without diabetes has not been previously considered. The objecti...

T he Affordable Care Act (ACA), signed into law by President Obama in March 2010, provides for comprehensive health reform in the United States. A major part of the ACA includes insurance reforms designed to make adequate and affordable health insurance accessible to nearly everyone. Five years after the ACA became law, and 1 year after major insurance reforms took effect , we discuss in this a...

OBJECTIVES Simultaneously define diet, physical activity, television (TV) viewing, and sleep duration across cardiometabolic disease groups, and investigate clustering of non-diet lifestyle behaviours. DESIGN Cross-sectional observational study. SETTING 22 UK Biobank assessment centres across the UK. PARTICIPANTS 502,664 adults aged 37-63 years old, 54% women. 4 groups were defined based ...

OBJECTIVE To assess the cost implications of diabetes prevention, it is important to know the lifetime medical cost of people with diabetes relative to those without. We derived such estimates using data representative of the U.S. national population. RESEARCH DESIGN AND METHODS We aggregated annual medical expenditures from the age of diabetes diagnosis to death to determine lifetime medical...

Damage to the autonomic nervous system results in changes in the heart rhythm and rate. Diabetes associated cardiovascular changes related to autonomic nervous system damage may be present anytime prior to manifestation of diabetes. Testing for changes to heart rhythm may provide a means of early identification of cardiovascular disease and allow timely intervention. Identification of cardiac a...

objective: international diabetes organization estimates that there are 285 million people worldwide who suffer from diabetes, and this figure is expected to increase to 450 million in next 20 years. according to statistics issued by the world health organization, diabetes is considered among ten leading causes of death in world and its prevalence in the population is growing.this paper deals w...

background: diabetes mellitus (dm) is a health concern which leads to complications such as retinopathy. pakistan has 6.9 million people living with dm and this toll will be doubled by 2025. objective: to determine serum il-6 and il-17 of type 2 diabetes mellitus (t2dm) patients with retinopathy. methods: in this cross-sectional casecontrol study, 212 subjects enrolled which were categorized in...

BACKGROUND People with diabetes who experience an acute myocardial infarction (AMI) have a higher risk of death and recurrence of AMI. This study was commissioned by the Department for Transport to develop survival tables for people with diabetes following an AMI in order to inform vehicle licensing. METHODS A cohort study using data obtained from national hospital admission datasets for Engl...