Hydrofluorocarbons and perfluorocarbons (F-gases) play a substantial role in global warming via the greenhouse effect thus have been under increased investigation recently. EU member states, including Czech Republic, already measures limiting F-gas use based on their GWP such as regulation No. 517/2014. This manuscript explains current status of emissions describes methodology estimation for ye...

This article reports the development and evaluation of two nano-emulsions (F45T-03/HFB and F15T-03/PFOB) containing fluorinated trityl radicals dissolved in perfluorocarbons. Preparation with a high-pressure homogenizer conferred sub-micronic size to both nano-emulsions. In vitro and in vivo EPR spectroscopy showed that the nano-emulsions had much greater oxygen sensitivity than the hydrophilic...

The aging mechanisms of perfluorocarbon emulsions were investigated using image analysis. Oil-in-water emulsions of two perfluorocarbons, n-perfluorohexane and perfluorodecalin, were prepared with three emulsifiers, Lecithin, Span 20, and Pluronic F-68. The effect of the temperature and the replacement of water by an aqueous phase consisting of a microbial culture medium were also studied. The ...

The oxygen transport capacity of fluorocarbons was investigated in the hamster chamber window model microcirculation to determine the rate at which oxygen is delivered to the tissue in conditions of extreme hemodilution [hematocrit (Hct) 11%]. Hydroxyethlyl starch (HES 200; 200 kDa molecular mass) was used as a plasma expander for two isovolemic hemodilutions performed with 10% HES 200 until a ...

BACKGROUND Perfluorocarbons (PFCs) are promising blood substitutes because of their chemical inertness and unparalleled ability to transport and upload O2 and CO2. Here, we report that PFC emulsions also efficiently absorb and transport nitric oxide (NO). METHODS AND RESULTS Accumulation of NO and O2 in PFC micelles results in rapid NO oxidation and generation of reactive NO(x) species. Such ...