The distribution of 32 per/polyfluoroalkyl substances (PFASs) in surface soils was determined at 62 locations representing all continents (North America n = 33, Europe n = 10, Asia n = 6, Africa n = 5, Australia n = 4, South America n = 3 and Antarctica n = 1) using ultra performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) systems. Quantifiable levels of perfluoroalkyl carbo...

First posted March 17, 2023 For additional information, contact: Director, Ohio-Kentucky-Indiana Water Science CenterU.S. Geological Survey5957 Lakeside BoulevardIndianapolis, IN 46278-1996Contact Pubs Warehouse Groundwater samples were collected during 2019 and 2020 from 23 wells in the Great Miami buried-valley aquifer (GM-BVA) southwestern Ohio by U.S. Survey, cooperation with Conservancy Di...

Perfluorooctane sulfonate (PFOS), a ubiquitous environmental pollutant, is neurotoxic to mammalian species. However, the underlying mechanism of its neurotoxicity was unclear. We hypothesized that PFOS suppresses BDNF expression to produce its neurotoxic effects by inhibiting the ERK-CREB pathway. SH-SY5Y human neuroblastoma cells were exposed to various concentrations of PFOS to examine the ro...

Perfluorooctane sulfonate (PFOS) is an emerging persistent pollutant which shows multiple adverse health effects. However, the neurotoxicity of PFOS and its mechanisms have not been fully elucidated. Using a combination of in vivo and in vitro methods, the present study provides a detailed description of PFOS-induced neurotoxicity. Results showed that the median lethal concentration of PFOS was...

Perfluorooctane sulfonate (PFOS) is under increased scrutiny asanenvironmentalpollutantduetorecentreportsof itsworldwide distribution, environmental persistence, and bioaccumulation potential. The susceptibility of technical PFOS and PFOS branched isomers to chemical reductive dehalogenation with vitamin B12 (260 μM) as catalyst and Ti(III)-citrate (36 mM) as bulk reductant in anoxic aqueous so...

Toxicity reference values (TRVs) and predicted no effect concentrations (PNECs) were derived for perfluorooctane sulfonate (PFOS) based on the characteristics of a top avian predator. On the basis of the protective assumptions used in this assessment, the benchmarks are protective of avian populations and were based on acute and chronic dietary exposures of northern bobwhite quail and mallard. ...