INTRODUCTION Critically ill immunocompromised (CIIC) patients with pulmonary infection are a population at high risk for invasive pulmonary aspergillosis (IPA). The host defenses are important factors to consider in determining the risk and outcome of infection. Quantification of changes in the status of host immunity could be valuable for clinical diagnosis and outcome prediction. METHODS We...

Immune-mediated polyarthritides (PA) are defined by synovial inflammation, failure to identify a microbial aetiology and response to immunosuppressive therapy. These diseases have common immunopathogenic features and may be subdivided into erosive (e.g., rheumatoid arthritis [RA]) and non-erosive forms (e.g., “idiopathic“ polyarthritis (IPA) type I; type II associated with infectious disease; t...

Perturbation analysis (PA) is a sample path technique for analyzing changes in the performance of stochastic systems due to changes in system parameters. In terms of stochastic simulation | the main setting for the application of PA | the objective is to estimate sensitivities of the performance measures of interest with respect to system parameters while obtaining estimates of performance itse...

Pada organisasi perusahaan jasa, dalam hal ini adalah hotel, mengevaluasi kepuasan konsumen yang penting untuk dilakukan karena dapat berdampak pada loyalitas konsumen. Kepuasan tercapai ketika pengukuran kinerja diharapkan oleh memiliki nilai lebih besar dibandingkan dengan aktual. Penelitian bertujuan kualitas pelayanan diberikan kepada tamu salah satu hotel berbintang 4 di Banyuwangi menggun...

Mabul Island is a popular diving site for divers, with its main appeal of marine life as one the most visited islands in Malaysia. If island not protected from tourist activities, image destination may deteriorate. This research focuses on measuring tourism competitiveness by evaluating sustainable features using Importance Performance Analysis (IPA). The aim to identify essential and evaluate ...

We provide an overview of the recently developed general infinitesimal perturbation analysis (IPA) framework for stochastic hybrid systems (SHSs), and establish some conditions under which this framework can be used to obtain unbiased performance gradient estimates in a particularly simple and efficient manner. We also propose a general scheme for systematically deriving an abstraction of a dis...