Introduction: Studies have shown the regulatory role of Leptin in bone formation, its expression in adipose tissue as well as increased levels in circulation following the adminstration of inflammatory stimuli such as lipopolysaccharides (LPS). However, there is little data evaluating the role of Leptin in inflammatory periapical lesions. The aim of this study was to evaluate the presence and c...

INTRODUCTION Most clinical studies on the outcome of apical surgery concentrate on periapical healing based on radiographic and clinical characteristics (signs and symptoms). This study focuses on long-term changes in periodontal parameters after apical surgery. METHODS Periodontal parameters (ie, probing depth [PD], level of gingival margin [GM], and calculated clinical attachment level [CAL...

INTRODUCTION Studies have shown the regulatory role of Leptin in bone formation, its expression in adipose tissue as well as increased levels in circulation following the adminstration of inflammatory stimuli such as lipopolysaccharides (LPS). However, there is little data evaluating the role of Leptin in inflammatory periapical lesions. The aim of this study was to evaluate the presence and co...

* Assistant Professor, College of Dental Surgery, B.P. Koirala Institute of Health Sciences, Dharan, Nepal ** Bacteriologist, Govt Medical College and Hospital, Patiala, Punjab, India INTRODUCTION Periapical pathosis is considered as an endogenous infection caused by oral microflora. Bacterial infection of dental pulp results in pulpal destruction and subsequently stimulates an inflammatory cel...

Periapical tissue from 58 cases requiring periapical surgery was examined histologically and cultured for the presence of microbes. Twenty-nine had a possible oral cavity communication and 29 did not. Approximately one-half of each biopsy was submitted for culture while the other portion was examined histologically. Cultures were positive for the presence of bacteria in 51 of 58 cases while bac...

Dental traumatic injuries may affect the teeth and alveolar bone directly or indirectly. Pulpal necrosis and chronic and apical periodontitis with cystic changes are the most common sequelae of the dental traumatic injuries, if the teeth are not treated immediately. This case report focuses on the conventional and surgical management of mandibular central incisors. A twenty-four-year-old male p...

Odontogenic infections can result from several conditions, such as pulp necrosis, periodontal disease, pericoronitis, trauma, or surgery.  The three types of odontogenic dental abscesses are endodontal periapical, periodontal, and pericoronal, depending on where the infection first developed. Periodontal abscesses, which particularly common in people with untreated disease patients during ...

Periapical lesions of endodontic origin may develop asymptomatically and become extensive. Treatment options to manage such lesions range from non-surgical root canal treatment and/or apical surgery to extraction. A high percentage of complete and partial healing of extensive perapical lesions following conventional endodontic therapy has been reported. The case reports in this article describe...