Purpose. The aim of this study was to analyse the levels of interleukin-6 (IL-6) and interleukin-8 (IL-8) in gingival crevicular fluid (GCF) of patients with chronic periodontitis prior to and following surgical and/or nonsurgical periodontal therapy for a period of 32 weeks. Methods. GCF samples were obtained from 24 nondiseased and 72 diseased sites of 12 periodontal patients prior to as well...

Perforation of teeth through the continuous epithelial lining of the oral cavity is a singular anatomical situation. The dental surface consists of hard tissues that lack the potential to renew themselves and to shed their superficial layer. The microecologic system of the oral cavity is colonised by more than 400 different bacterial species (Moore and Moore, 1994). Approximately 150 or more di...

Repair of tooth supporting alveolar bone defects caused by periodontal and peri-implant tissue destruction is a major goal of reconstructive therapy. Oral and craniofacial tissue engineering has been achieved with limited success by the utilization of a variety of approaches such as cell-occlusive barrier membranes, bone substitutes and autogenous block grafting techniques. Signaling molecules ...

1.1 Regenerative periodontal therapy The goal of periodontal therapy is to improve periodontal health and thereby to satisfy the patient’s esthetic and functional needs or demands. To achieve this goal, most periodontal treatments aim to reduce probing depths and maintain or improve attachment levels and these parameters are used as surrogates of improved tooth retention. Conventional periodont...

Introduction: An acquired diastema may be a warning sign signaling advanced periodontitis. Gingival inflammation, reduced bony support, and tooth mobility contribute to the drifting of teeth, condition called pathologic migration, formed gap or space between two teeth more. Identification causative factors involved in migration is crucial for successful treatment. Case Management: 1 - A 38-year...

Periodontal disease is associated with endothelial dysfunction of the brachial artery and hemodynamic alterations of the common carotid artery. Periodontal therapy improves endothelial function. It is not known if it is able also to improve the hemodynamics of the carotid artery. The aim of the current study was to evaluate the efficacy of 2 different periodontal treatments on carotid hemodynam...

BACKGROUND Host responses to periodontal disease include the production of different enzymes that are released by stromal, epithelial or inflammatory cells. There are important enzymes associated with cell injury and cell death like: aspartate and alanine aminotransferase (AST, ALT), lactate dehydrogenase (LDH), creatine kinase (CK), alkaline and acidic phosphatase (ALP, ACP), gama glutamyl tra...

OBJECTIVES To evaluate the influence of periodontal therapy on glycosylated hemoglobin and fasting blood glucose and serum levels of interleukin (IL)-4, IL-6, IL-8, IL-10, and tumor necrosis factor-alpha (TNF-α) in chronic periodontitis (CP) patients with type-2 diabetes mellitus (T2DM) and in controls. METHODS A total of 30 periodontal patients, 15 of which were systemically healthy (control...

background: chronic renal failure patients undergoing hemodialysis are susceptible to periodontal diseases due to systemic complications of the disease and using different drugs. the present study investigated the periodontal status of patient’s who underwent hemodialysis, in babol, northern iran. methods: one-hundred-fifteen hemodialysis patients (63 males, 52 females) with the mean age of 47....

AIM This study examined the predictors of loss to follow-up in long-term supportive periodontal therapy in patients with chronic periodontitis. METHODS A total of 280 patients with moderate to severe chronic periodontitis in a tertiary care hospital in China were investigated and followed over the course of study. Questionnaires on clinical and demographic characteristics, self-efficacy for o...