PURPOSE To determine the agreement between Spectralis and Cirrus spectral domain optical coherence tomography (SD-OCT) measurements of peripapillary retinal nerve fiber layer (RNFL) thickness. METHODS Suspected or confirmed cases of glaucoma who met the inclusion criteria underwent peripapillary RNFL thickness measurement using both the Spectralis and Cirrus on the same day within a few minut...

Purpose To evaluate peripapillary microvascular changes in patients with primary open-angle glaucoma (POAG) after trabeculectomy using optical coherence tomography (OCT) angiography, and to determine the influence of lamina cribrosa (LC) displacement on changes in peripapillary microvasculature. Methods The peripapillary retinal microvasculature and LC were imaged using OCT angiography and OC...

Optic nerve head drusen can be associated with peripapillary choroidal neovascularization, in both the pediatric and adult population. These membranes can involve the macula, causing significant visual loss. Herein, we present a case that required treatment with an anti-VEGF agent. The patient failed to respond to the initial agent, but subsequently responded to a change of agent. Adult patient...

PURPOSE To develop structural markers of early glaucomatous optic nerve damage with confocal scanning laser ophthalmoscopy. METHODS Custom software was developed to analyze the images of 53 patients with open-angle glaucoma and 43 healthy subjects (matched for age, race, and refractive error), with images acquired with a confocal scanning laser ophthalmoscope. Height values were obtained alon...

1 Purpose: The posterior sclera has a major biomechanical influence on the optic nerve 2 head, and may therefore be important in glaucoma. Scleral material properties are 3 influenced significantly by collagen fiber architecture. Here we quantitatively map fiber 4 orientation in non-glaucoma and glaucoma posterior human scleras. 5 Methods: Wide-angle x-ray scattering quantified fiber orientatio...

We evaluated the relationship between the size of the peripapillary crescent and the axial length (AL) of the eye as well as the fine structure of the peripapillary crescent in selected eyes. Infrared fundus imaging and spectral domain optical coherence tomography (SDOCT) (Spectralis HRA+OCT, Heidelberg Engineering, Germany) centered at the fovea were performed on 72 healthy adults. On the infr...

The purpose of this study is to evaluate the macular ganglion cell layer (GCL) and peripapillary retinal nerve fibre layer (RNFL) thickness in patients with unilateral posterior cerebral artery (PCA) ischaemic lesions using spectral-domain optical coherence tomography (SD-OCT). A prospective, case-control study of patients with unilateral PCA lesion was conducted in the neuro-ophthalmology clin...

We analyzed the vascular densities (VDs) of optic disc areas in eyes with normal-tension glaucoma (NTG) according to their branch retinal vessel occlusion (BRVO) status. The VDs discs and peripapillary 68 NTG patients BRVO (BRVO group; fellow eyes) 37 alone (control were measured on angiographic images obtained via swept-source optical coherence tomography angiography. compared among groups cor...

Purpose To compare optical coherence tomography angiography (OCT-A) retinal vasculature measurements between nonarteritic anterior ischemic optic neuropathy (NAION) and open angle glaucoma (OAG) with altitudinal hemifield visual field defects. Methods This retrospective cross-sectional study included 10 NAION eyes and 16 OAG eyes, both demonstrating hemifield visual field defects, and 27 norm...