GBM is the most common primary brain tumor, but intraventricular GBM is rare and only few cases have been reported in the literature. The authors report a case of 64-year-old man who had a remote history of previous periventricular intracerebral hemorrhage. Brain computed tomography (CT) and magnetic resonance (MR) imaging showed an intraventricular lesion with inhomogeneous enhancement, infilt...

Wernicke’s encephalopathy (WE) is a neurological disorder associated with thiamine deficiency (1). Patients may present with a classic triad of symptoms consisting of altered mental status, ataxia, and ocular dysfunction. Diagnosis can be difficult as clinical presentation is not typical in certain cases. WE is curable if thiamine is administered parenterally early in the course of the disease,...

INDIAN PEDIATRICS 54 VOLUME 44JANUARY 17, 2007 Patent ductus arteriosus (PDA) is a common occurance in preterm infants with significant morbidities. Indomethacin, has been widely used to treat hemodynamically significant PDA. However, this agent can cause adverse reactions such as reduced renal, mesenteric, and cerebral perfusion leading to transient or permanent renal dysfunction, necrotizing ...

Periventricular hemorrhagic infarct (PVHI) is among the most devastating injuries suffered by prematurely born infants. In PVHI (formerly called Grade 4 intraventricular hemorrhage), an intraventricular vein that drains smaller veins from the surrounding white matter is occluded, resulting in venous infarction with hemorrhage [1]. DTI has become a useful imaging technique to identify maturation...

BACKGROUND AND PURPOSE Leukoaraiosis (LA) is associated with dementia, ischemic stroke, and intracerebral hemorrhage (ICH), but there are few data on how LA might impact outcomes after acute ICH. We tested the hypothesis that the severity of LA on magnetic resonance imaging is related to worse functional outcomes after spontaneous ICH. METHODS We prospectively identified patients with spontan...

We studied 33 consecutive patients with computed tomographic findings of decreased density in the periventricular white matter (leukoaraiosis). Computed tomograms in five (aged 56-75 years) of the 33 demonstrated intracerebral hematoma. The hemorrhages were situated in the thalamic area in four and in the parietotemporal area in one patient. These five patients were hypertensive and had signs c...

Drs Cooke and Morgan have shown in a double blind trial that ethamsylate seemed to reduce the incidence of periventricular haemorrhage.' Although this is of great interest, no confirmation of these results is available so far. Yet Delandale Laboratories are already advertising ethamsylate as the drug to prevent periventricular haemorrhage in the newborn infant. In the past similar effects, clai...

INTRODUCTION Major advances in perinatal care over the latest decades have increased the survival rate of extremely premature infants. Centralisation of perinatal care was implemented in Denmark from 1995. This study evaluates the effect of organisational changes of perinatal care on survival and morbidity of live-born infants with gestational ages (GA) of 22-28 weeks. METHODS Three cohort st...