نتایج جستجو برای: pet oligomers
تعداد نتایج: 63221 فیلتر نتایج به سال:
Synthesis of stereoregular DNA methylphosphonates has been accomplished for homo-oligomers, but remains a formidable problem for oligomers of a defined antisense target sequence. In this work, four trimer and tetramer deoxynucleoside methylphosphonates of mixed sequence (dACA, dCCAA, dAGGG, and dGCAT) were prepared by block coupling of diastereomerically pure dimers with either monomers or othe...
β-amyloid (Aβ) oligomers have been closely implicated in the pathogenesis of Alzheimer's disease (AD). We found, for the first time, that bis(heptyl)-cognitin, a novel dimeric acetylcholinesterase (AChE) inhibitor derived from tacrine, prevented Aβ oligomers-induced inhibition of long-term potentiation (LTP) at concentrations that did not interfere with normal LTP. Bis(heptyl)-cognitin also pre...
Background: Age-related neurodegenerative diseases share a number of important pathological features, such as accumulation of misfolded proteins as amyloid oligomers and fibrils. Recent evidence suggests that soluble amyloid oligomers and not the insoluble amyloid fibrils may represent the primary pathological species of protein aggregates. Results: We have produced several monoclonal antibodie...
Carbon foams were synthesized from blends of coal and several C-containing additives different nature, with the aim to study their influence on foaming step, hence in final properties obtained foams. The included biomass agricultural products, thermoplastic thermosetting polymers, at concentrations, ranging 5 20 wt%. effects pore structure, carbon matrix thermal resulting investigated. presence...
objective(s): the aim of this study was to analyze detection rates and effectiveness of 18f-fluorodeoxyglucose positron emission tomography (fdg-pet) cancer screening program for prostate cancer in japan, which is defined as a cancer-screening program for subjects without known cancer. it contains fdg-pet aimed at detection of cancer at an early stage with or without additional screening tests ...
background: to retrospectively describe imaging characteristics of liver metastases on fused fdg-pet/ mri data sets and to compare the diagnostic accuracy of mri and fused fdg-pet/mri data sets for the detection of liver metastases in patients undergoing systemic anticancer treatment. materials and methods: 43 oncological patients (mean age: 56+/- 11 years) were investigated by fdg-pet/ct and l...
pp/pep blends, because of different solubility factors, are incompatible. the aim of this research was to use pp-g-ma compatibilizer in a two-component blend. after preparing this compatibilizer in internal mixer and investigating different parameters on producing process, optimum compatibilization was obtained. pp/pet (60/40) blend fibers with different percentages of this compatibilizer in tw...
There are some aspects of the proteins «self-organization» that not well studied, understanding relationship between conformational folding linked with formation a disulfide bond is important and challenging both from biophysical biochemical perspectives. Studies have attempted to elucidate role thiol groups in maintenance native conformation activity arginase I II different organ origin. It wa...
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