OBJECTIVES The goal was to estimate the prevalence of laryngopharyngeal reflux (LPR) in patients with laryngeal and voice disorders. STUDY DESIGN AND SETTING This was a prospective study of 113 unselected, new patients with laryngeal and voice disorders. Patients completed an extensive medical history form including a reflux symptom profile. A comprehensive otolaryngologic examination was per...

Sorption of dissolved strontium on kaolinite, amorphous silica, and goethite was studied as a function of pH, aqueous strontium concentration, the presence or absence of atmospheric CO(2) or dissolved phosphate, and aging over a 57-day period. Selected sorption samples ([Sr(aq)](i) approximately 0.5-1x10(-3) m) were examined with synchrotron X-ray absorption spectroscopy (XAS) at low (13-23 K) ...

The possible effects of ocean acidification on growth, organic tissue and protein profile in the bryozoan Myriapora truncata (Pallas, 1766) were studied in samples transplanted along a gradient of different pH conditions in an area of natural volcanic CO2 vents at Ischia Island (Tyrrhenian Sea, Italy). Living colonies from normal (mean pH 8.10), intermediate (pH 7.83) and low (pH 7.32) pH sites...

aim to offer immediate help to those who most need it. Usually, there is no urge to start a systematic registration on demographic data of clients and on characteristics of interventions. Nevertheless, there is a growing necessity to do so. Structured gathering of information can help professionals to obtain insight in the age, sex and number of clients they see, in the usefulness of the interv...

We have performed a genome-wide analysis of common genetic variation controlling differential expression of transcript isoforms in the CEU HapMap population using a comprehensive exon tiling microarray covering 17,897 genes. We detected 324 genes with significant associations between flanking SNPs and transcript levels. Of these, 39% reflected changes in whole gene expression and 55% reflected ...

Stillbirths contribute substantially to perinatal mortality in developed countries with a prevalence ranging between 4 and 6 per 1000 births (1-3). Despite careful evaluation during pregnancy of fetal well-being, about 25-50%, 1 remains without a clear cause, coding for a new entity called Sudden Intrauterine Unexplained Death Syndrome (SIUDS). Moreover, an important cause of early sudden death...

Hemodynamic (blood flow rate, hematocrit, hemoglobin concentration, and blood viscosity) and pH responses to glucose (6 g/kg, i.p.) injections were studied in ten Walker 256 carcinoma tumors (0.5-1.8 g) grown in the "tissue-isolated" tumor preparation. A maximum blood flow reduction of 57 +/- 19% (SD) occurred concurrently with an increase in tumor arterial-venous blood pH difference 20-30 min ...

We have performed a genome-wide analysis of common genetic variation controlling differential expression of transcript isoforms in the CEU HapMap population using a comprehensive exon tiling microarray covering 17,897 genes. We detected 324 genes with significant associations between flanking SNPs and transcript levels. Of these, 39% reflected changes in whole gene expression and 55% reflected ...