Type II Na/P(i) cotransporters play key roles in epithelial P(i) transport and thereby contribute to overall P(i) homeostasis. Renal proximal tubular brush border membrane expresses the IIa isoform, whereas the IIb isoform is preferentially expressed in small intestinal brush border membrane of mammals. IIa and IIb proteins are predicted to contain eight transmembrane domains with the N- and C-...

BACKGROUND & OBJECTIVE In India, National AIDS Control Organization (NACO) introduced syndromic approach to treat patients with abnormal vaginal discharge without a need for laboratory tests. Simple tools like pH test and Whiff test can be done without high expertise, microscope and even speculum. This can improve diagnostic value of syndromic approach of abnormal vaginal discharge. The present...

Article history: Received 15 August 2011 Received in revised form 6 October 2011 Accepted 25 October 2011 Available online 15 December 2011 0026-2714/$ see front matter 2011 Published by doi:10.1016/j.microrel.2011.10.026 ⇑ Corresponding author at: Biosensor Group, Biom Center, Chang Gung University, 259 Wen-Hwa 1st Roa Taiwan. Tel.: +886 3 2118800x5786. E-mail address: [email protected] (C...

There is evidence for the existence of developmental changes in expression of troponin I (TNI) in cardiac thin filaments; however, regulation of TNI expression has not been described. We tested whether thyroid state affects expression of TNI using neonatal and adult rats made hypothyroid by treatment with 6-n-propyl-2-thiouracil. Polyacrylamide gels of myofibrils from hearts of 7-, 14-, 21-, an...

There is evidence for the existence of developmental changes in expression of troponin I (TNI) in cardiac thin filaments; however, regulation of TNI expression has not been described. We tested whether thyroid state affects expression of TNI using neonatal and adult rats made hypothyroid by treatment with 6-n-propyl-2-thiouracil. Polyacrylamide gels of myofibrils from hearts of 7-, 14-, 21-, an...

Supramolecular nanogels cross-linked by host-guest interaction between dextran grafted benzimidazole (Dex-g-BM) and thiol-β-cyclodextrin were designed. Their special supramolecular pH-sensitivity under acidic conditions (pH < 6, within the range of malignant cellular endosomes) and reduction sensitivity in response to biologically relevant stimuli will be of great advantage to the future of can...

The effects of acidosis on the myocardial sensitivity to verapamil and nifedipine were examined by measuring the changes in tension in cat papillary muscles perfused in oxygenated physiological saline. Calcium concentration was altered over a range of 2 to 12 mmol . litre-1 and pH adjusted to 7.4, 6.8 or 6.0. Addition of verapamil or nifedipine moved the calcium dose response to the right. At p...

Here we report the fabrication and characterization of pH sensors using aligned single-walled carbon nanotubes (SWNTs). The SWNTs are dispersed in deionized (DI) water after chemical functionalization and filtration. They are deposited and organized on silicon substrates with the dielectrophoresis process. Electrodes with "teeth"-like patterns-fabricated with photolithography and wet etching-ar...

BACKGROUND The RightSpotpH™ indicator is a new device designed to facilitate pH-based confirmation of nasogastric tube placement while minimizing exposure of the operator to nasogastric contents. STUDY OBJECTIVES In vivo and in vitro validation of the RightSpotpH™ indicator. FINDINGS Patients (23) undergoing general anesthesia had placement of a nasogastric tube and gastric pH electrode cat...

Background: The RightSpotpHTM indicator is a new device designed to facilitate pH-based confirmation of nasogastric tube placement while minimizing exposure of the operator to nasogastric contents. Study objectives: In vivo and in vitro validation of the RightSpotpHTM indicator. Findings: Patients (23) undergoing general anesthesia had placement of a nasogastric tube and gastric pH electrode ca...