In the conditioned place preference test, phencyclidine (PCP) produces place aversion in naive rats, whereas PCP produces place preference in rats treated with PCP repeatedly. Although the PCP-induced place aversion is thought to involve the serotonergic system, the mechanisms of the PCP-induced place preference are unclear. We investigated whether the dopaminergic system is involved in place p...

Phencyclidine (PCP) has been a street drug of waxing and waning popularity since 1965, when investigation into its use as a human preanesthetic agent was discontinued because of severe behavioral side effects. Phencyclidine is not a hallucinogen nor a psychedelic but rather is described as a dissociative anesthetic. It appears to short-circuit the ability to interpret ordinary external proprioc...

In this issue of Cell, identify a first regulatory link between planar cell polarity (PCP) signaling and apical-basal polarity. The authors propose that a component of the apical Crumbs complex regulates the phosphorylation of the Frizzled (Fz) PCP receptor, thus modulating PCP in the Drosophila eye.

Due to the mispricing of options, no-arbitrage condition put-call parity (PCP) violations lead to inefficiency in the currency options market. Through transaction costs, the effects of these violations are reduced to negligible levels, indicating that PCP is not a sufficient condition for an options market efficiency test. Thus, this study developed a transaction cost-adjusted put-call parity (...

We study degenerate curves in pseudo-Euclidean spaces of index two by introducing the Cartan reference along a degenerate curve. We obtain several different types of degenerate curves and present existence, uniqueness and congruence theorems. We also give some examples of such a curves in low dimensions.

This paper presents retention behavior and mass spectra of eluting peaks for twelve phenyl and thienyl analogues of phencyclidine (PCP) as well as PCP itself. An on-column decomposition product common to all thienyl analogues is described. Finally, a practical analytical procedure is given for the detection and identification of these compounds in low (under 5 ng/mL) concentrations in urine.

BACKGROUND The last decade has witnessed a significant move towards new modes of governing that are based on coordination and collaboration. In particular, local level partnerships have been widely introduced around the world. There are few comprehensive approaches for researching the effects of these partnerships. The aim of this paper is to outline a network approach that combines structure a...

ABEL A. BUSTAMANTE1, CRISTINA L. SCIOSCIA2 & MARÍA E. CASANUEVA1 1Universidad de Concepción, Facultad de Ciencias Naturales y Oceanográficas. Departamento de Zoología. Casilla 160-C, Concepción, Chile. E-mail: [email protected]; [email protected] 2División Aracnología, Museo Argentino de Ciencias Naturales “Bernardino Rivadavia”, Av. Angel Gallardo 470, C1405DJR Buenos Aires, Argentina. E-m...