Dry age-related macular degeneration and Stargardt disease undergo a known toxic mechanism caused by carbonyl oxidative stresses (COS). This is responsible for accumulation in the retinal pigment epithelium (RPE) of A2E, main pyridinium bis-retinoid lipofuscin component. Previous studies have shown that stress cells could be reduced an alkyl-phloroglucinol-DHA conjugate (lipophenol). Here, we p...

The asymmetric unit of the title compound, C(10)H(14)N(4)·C(6)H(6)O(3)·H(2)O, contains one mol-ecule of benzene-1,3,5-triol, two half-molecules of 1,1'-butane-1,4-diyldi-1H-imidazole (each molecule is centrosymmetric) and one solvent water mol-ecule. In the crystal structure, inter-molecular O-H⋯O and O-H⋯N hydrogen bonds link all mol-ecules into a three-dimensional supra-molecular network.

greenhouse-grown red pine seedling, Pinus resinosa, when cultured on malt agar or potato dextrose agar (PDA) showed inhibitory activity against selected test fungi. Sensitive fungi included Ceratocystis ulmi (BUISM.) C. MOREAU, Pythium spp., Rhizoctonia solani KUHN, Cylindrocarpon sp., Fusarium oxysporum SCHLECT., and Sirococcus strobilinus PREUSS. When grown on PDA, a colorless crystalline sol...

A new sulfate-reducing bacterium was isolated from marine sediment with hydroxyhydroquinone (1,2,4-trihydroxybenzene) as the sole electron and carbon source. Strain HHQ 20 grew slowly with doubling times of > 20 h and oxidized hydroxyhydroquinone, lactate, pyruvate, ethanol, fructose, and ribose incompletely to acetate and carbon dioxide, with concomitant reduction of sulfate to sulfide. Cells ...

Strategies to manage metabolic hydrogen ([H]) in the rumen should be considered when reducing ruminant methane (CH4) emissions. However, little is known about the use of dietary treatments to stimulate rumen microorganisms capable of capturing the [H] available when CH4 is inhibited in vivo. The effects of the phenolic compound phloroglucinol on CH4 production, [H] flows and subsequent response...

Background: To compare the effects of Dilapan-S versus phloroglucinol on cervical dilation in hysteroscopic polyp resection. Methods: This prospective, observational study enrolled non-menopausal patients with endometrial polyps who underwent operative hysteroscopy for transcervical resection between October 2021 and 2022. The were given or dilation. primary outcome was time; secondary outcomes...