Phoma black stem and leaf spot disease (Phoma medicaginis) not only destroys annual Medicago spp. forage seed yield but also reduces herbage quality by consequent phytoestrogen production that ovulation of grazing animals. Two controlled environment studies evaluated the effects plant developmental stage in rugosa ‘Paraponto’ M. scutellata ‘Sava’ different inoculum concentrations P. medicaginis...

Previously, flaviolin was isolated from the blackish culture solution of Phoma wasabiae [1]. In continuation of the study on the metabolites of this mold, we have now isolated 2-hydroxy-6-methoxy-3,5-dimethyl-l,4-benzoquinone. This benzoquinone was already synthesized [2], but has not been found as a natural product. In this paper we wish to report on the isolation of the above quinone from the...

In this research,for taxonomic studies and identification of the fungi associated with the powdery mildew(Oidium euonymi- japonici) of Buxus trees (Euonymus japonica), the infected leaves were collected during autumn and winter 2012-2013 in Gorgan (Golestan province -Iran). The samples after washing and surface sterilizing, were cultured on PDA medium(with boxwood extract).Then based on availab...

Two new polyketides, arthropsadiol C (1) and massarilactone H (2), together with six known derivatives (3-8) were isolated from the culture broth of the marine-derived fungus Phoma herbarum. Their structures were elucidated on the basis of spectroscopic methods, including 2D NMR techniques. Compounds 2, 4, 5, and 8 showed moderate neuraminidase inhibitory activity with IC(50) values ranging fro...

Through our screening for novel antifungal compounds, YM-215343 was found in the culture extract of Phoma sp. QN04621. The structure of YM-215343 was determined by several spectroscopic experiments as a novel compound closely related to apiosporamide and fischerin. YM-215343 exhibited antifungal activity against the pathogenic fungi, Candida albicans, Cryptococcus neoformans and Aspergillus fum...

Incorporation of [l3C,2H3-CHs]-L-methionine into cytochala-: sin A (I), cytochalasin B (II), proxiphomin (III) and protophomin (IV) by Phoma exiqua var. exiqua demonstrated that the two C-methylations occur with retention of all three H-atoms of the methyl group. Conclusions are drawn concerning the stage of the methylation reaction during the biogenetic pathway. On the basis of the results amo...

Endophytic fungi were isolated from various tissues (root, stem, petiole, leaf, and fl ower stalk) of 3- and 4-year-old ginseng plants (Panax ginseng Meyer) cultivated in Korea. The isolated endophytic fungi were identified based on the sequence analysis of the internal transcribed spacer (ITS), 1-5.8-ITS 2. A morphological characterization was also conducted using microscopic observations. Acc...