Definitions of healthy ageing include survival to a specific age, being free of chronic diseases, autonomy in activities of daily living, wellbeing, good quality of life, high social participation, only mild cognitive or functional impairment, and little or no disability. The working group Epidemiology of Ageing of the German Association of Epidemiology organized a workshop in 2012 with the aim...

This research was carried out to study the effect of ageing on antioxidant and biochemical changes of wheat (Triticum aestivum L.) seeds. The experiment laid out in completely randomized design (CRD) with four replications in Islamic Azad University, Boroujerd Branch, Boroujerd, Iran in 2015. The seeds of wheat (cv Sardari) were harvested at maturity and ageing treatments were done at 43° C wit...

Ageing-related diseases are an important cause of mortality. Although the susceptibility to these diseases is partially genetically determined, a person’s physical activity level can influence the development of harmful alterations in the body through epigenetic pathways. Therefore, it is important to investigate both genetic and epigenetic aspects of ageing-related diseases. In this study, the...

This report has been put together for the Interreg IVB project: Biochar: climate saving soils The objectives for this report were: Objective 4.2.1: Systems to screen biochar–plant interactions-The effect of biochar on root architecture and the localisation of soil mineral nitrogen in the rhizosphere, characterized using mesocosms. Objective 4.2.2: Testing the simulation of physical ageing of bi...

Human immune senescence accompanies with the physical and physiological frailty. The functional change and shift of NK, NKT and T cell subsets by ageing have been widely studied. However, it remains largely unclear how the ageing and disease conditions affect the distribution of lymphocytes. In the present study, 233 subjects with age range from 20 to 87 year old, including healthy people, peop...

Cutaneous ageing is the result of two distinct, biological processes which may occur concurrently: (i) the passage of time, termed intrinsic ageing and (ii) environmental influences, termed extrinsic ageing. Intrinsic ageing of the skin is a slow process which causes changes in tissue structure and impairs function in the absence of additional biological, chemical and physical factors. The clin...

BACKGROUND Population ageing is a global phenomenon that has characterised demographic trends during the 20th and 21st century. The rapid growth in the proportion of older adults in the population, and resultant increase in the incidence of age-related cognitive decline, dementia and Alzheimer's disease, brings significant social, economic and healthcare challenges. Decline in cognitive abiliti...

Objective: We examined whether midlife body mass index (BMI) and waist circumference (WC) predict successful ageing. Design and Methods: BMI/WC were assessed in 4869 persons (mean age 51.2, range 42-63 in 1991/93) and survival and successful ageing (alive, no chronic disease at age >60 years, not in the worst ageand sex-standardized quintile of cognitive, physical, respiratory, and cardiovascul...

Reactive oxygen species (ROSs) are often associated with damage to cellular functions. ROSs production is indicatives of oxidative stress during physical exercise. Oxidative stress occurs in those circumstances in which free radicals determine a tissue damage or production of toxic and dangerous compounds for tissues. In a relaxation state, antioxidant defense of body may hold under control fre...